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IFNG — ITIH4
Text-mined interactions from Literome
Peruzzi et al., AIDS Res Hum Retroviruses 2000
:
Taken together these data suggest that ( 1 ) an inhibitory effect of gp120 may account for the NK cell dysfunction in HIV infected subjects ; ( 2 ) the
gp120 mediated decrease in
IFN-gamma production by NK cells may contribute to the cytokine imbalance observed in HIV infection ; and ( 3 ) VIP counteracts the inhibitory effect of gp120 on NK cell functions
Daly et al., Vaccine 2005
:
Conversely, antigen-specific
IFN-gamma production
induced by
gp120pDNA or HApDNA was reduced in IL-12-defective mice, whereas addition of plasmid DNA coding for IL-12 enhanced Th1 responses
Khan et al., J Neurovirol 2007
(HIV Infections...) :
Taken together, these findings showed that
gp120 , in the
presence of
IFN-gamma , can cause dysfunction of the blood-brain barrier endothelium via MAPK pathways involving several gp120-HBMEC interactions
Nair et al., Clin Diagn Lab Immunol 1995
:
However,
gp120 induced suppression of IFN-alpha and
IFN-gamma was significantly greater with CBL than with APBL
Dürrbaum-Landmann et al., J Leukoc Biol 1994
(HIV Infections) :
Interferon-gamma release of lymphocytes induced by purified protein derivative of tuberculin was
enhanced by
gp120
Van der Meide et al., Biotherapy 1996
(Inflammation) :
Gp120 as a sole agent significantly
suppressed IFN-gamma production by mitogen stimulated PBLs and induced the production of IFN-alpha in cultures of normal human peripheral blood mononuclear cells ( PBMCs )