Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Peruzzi et al., AIDS Res Hum Retroviruses 2000 : Taken together these data suggest that ( 1 ) an inhibitory effect of gp120 may account for the NK cell dysfunction in HIV infected subjects ; ( 2 ) the gp120 mediated decrease in IFN-gamma production by NK cells may contribute to the cytokine imbalance observed in HIV infection ; and ( 3 ) VIP counteracts the inhibitory effect of gp120 on NK cell functions
Daly et al., Vaccine 2005 : Conversely, antigen-specific IFN-gamma production induced by gp120pDNA or HApDNA was reduced in IL-12-defective mice, whereas addition of plasmid DNA coding for IL-12 enhanced Th1 responses
Khan et al., J Neurovirol 2007 (HIV Infections...) : Taken together, these findings showed that gp120 , in the presence of IFN-gamma , can cause dysfunction of the blood-brain barrier endothelium via MAPK pathways involving several gp120-HBMEC interactions
Nair et al., Clin Diagn Lab Immunol 1995 : However, gp120 induced suppression of IFN-alpha and IFN-gamma was significantly greater with CBL than with APBL
Dürrbaum-Landmann et al., J Leukoc Biol 1994 (HIV Infections) : Interferon-gamma release of lymphocytes induced by purified protein derivative of tuberculin was enhanced by gp120
Van der Meide et al., Biotherapy 1996 (Inflammation) : Gp120 as a sole agent significantly suppressed IFN-gamma production by mitogen stimulated PBLs and induced the production of IFN-alpha in cultures of normal human peripheral blood mononuclear cells ( PBMCs )