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JUN — NOTCH2
Text-mined interactions from Literome
Talora et al., Genes Dev 2002
(Cell Transformation, Neoplastic...) :
Increased Notch1 signaling, but not
Notch2 ,
causes a dramatic down-modulation of HPV-driven transcription of the E6/E7 viral genes, through suppression of
AP-1 activity by up-regulation of the Fra-1 family member and decreased c-Fos expression
Henken et al., Cellular oncology (Dordrecht) 2012
(Cell Transformation, Neoplastic...) :
Moderate
Notch expression
led to an increased
AP-1 transcriptional activity and DNA binding activity, but did not affect complex composition
Ordentlich et al., Mol Cell Biol 1998
:
We provide evidence that Notch and Deltex may act on E47 by inhibiting signaling through Ras because ( i ) full E47 activity was found to be dependent on Ras and ( ii ) both
Notch and Deltex
inhibited GAL4-Jun , a hybrid transcription factor whose activity is dependent on signaling from Ras to SAPK/JNK