Gene interactions and pathways from curated databases and text-mining

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MCOLN1 — PRKAR2A

Text-mined interactions from Literome

Paveto et al., Cell Biol Int Rep 1991 (Second Messenger Systems) : The effect of these hormones in permeabilized cells of the fungus produced a 2-3 fold increase in the Mg2+ , GTP dependent adenylyl cyclase activity as well as full activation of the cAMP dependent protein kinase (PKA) activity
Weinman et al., J Clin Invest 1993 : When assayed after reconstitution, PKA in the presence of ATP and Mg2+ did not inhibit Na ( + ) -H+ exchange transport in a fraction of solubilized BBM proteins eluting from an anion exchange column between 0.2 and 0.4 M NaCl ( fraction B )
Mita et al., Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1996 : The PKA activity required Mg2+ at concentrations between 2 and 10 mM