Gene interactions and pathways from curated databases and text-mining

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INS — NCL

Text-mined interactions from Literome

Terrasi et al., Int J Cancer 2009 (Breast Neoplasms...) : In contrast, nucleolin binding to Lep-2548G/A was downregulated in response to insulin , while it was not regulated on Lep-2548G/G
Csermely et al., J Biol Chem 1993 : Insulin induces the phosphorylation of nucleolin ... Insulin induces the serine phosphorylation of the nucleolar protein nucleolin at subnanomolar concentrations in differentiated 3T3-442A cells ... The cell-permeable casein kinase II inhibitor 5,6-dichlorobenzimidazole-riboside prevents the insulin stimulated phosphorylation of nucleolin suggesting that casein kinase II may mediate this effect of the hormone ... The dose dependence of insulin induced nucleolin phosphorylation and insulin stimulated RNA efflux from intact cell nuclei are almost identical