Gene interactions and pathways from curated databases and text-mining

◀ Back to EPHB2

EPHB2 — NFATC4

Text-mined interactions from Literome

Ichida et al., J Biol Chem 2001 : Pharmacological inhibition of MEK1 or expression of a dominant negative form of c-Raf or ERK2 inhibits phenylephrine stimulated NFAT3 activation
Chandrasekar et al., J Biol Chem 2008 : Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2 dependent NFATc4 phosphorylation ... These data demonstrate for the first time that IL-18 selectively suppresses adiponectin expression via ERK1/2 dependent NFATc4 activation and suggest that the inverse relationship observed between IL-18 and adiponectin in various chronic pathological conditions is causally related