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CDKN1A — NRAS
Text-mined interactions from Literome
VaquƩ et al., J Biol Chem 2005
(Leukemia...) :
c-Myc antagonized the
induction of
p21Cip1 mediated by oncogenic H-, K-, and
N-Ras and by constitutively activated Raf and ERK2
Haferkamp et al., Aging 2009
(Retinoblastoma) :
Furthermore, we show that although both p16(INK4a) and
p21 ( Waf1 ) are upregulated in
response to
N-RAS ( Q61K ), the activities of these CDK inhibitors are clearly distinct and only the loss of p16(INK4a) weakens senescence