Gene interactions and pathways from curated databases and text-mining

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IFNG — NUP43

Text-mined interactions from Literome

Nguyen et al., Biochem J 2000 : Here, we report that IFN-alpha/beta and IFN-gamma rapidly activate the JAK-STAT1 ( Janus kinase-signal transducer and activator transcription factor 1 ) and p42/44 mitogen activated protein kinase ( p42/44 MAPK ) in freshly isolated rat hepatocytes ... In contrast with the JAK-STAT signalling pathway, acute ethanol exposure significantly potentiated IFN-beta or IFN-gamma induced activation of p42/44 MAPK, and caused marked activation of protein kinase C ( PKC )
Sodhi et al., Glycoconj J 2007 : Pharmacological inhibitor of tyrosine kinase, PI3 kinase, protein kinase C, p42/44 , p38, JNK and intracellular calcium immobilizing agent down regulated the WGA induced expression of cytokines TNF-alpha, IL-1beta, IL-12 and IFN-gamma