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MAPK14 — PEBP1

Text-mined interactions from Literome

Trakul et al., J Biol Chem 2005 (MAP Kinase Signaling System) : Here, we show that RKIP inhibits MAPK by regulating Raf-1 activation ; specifically, RKIP acts subsequent to Raf-1 membrane recruitment, prevents association of Raf-1 and p21 activated kinase (PAK), and blocks phosphorylation of the Raf-1 kinase domain by PAK and Src family kinases ... Because c-Raf-1 and B-Raf are both required for maximal MAPK stimulation by epidermal growth factor in neuronal and epithelial cell lines, we determined whether RKIP significantly affects MAPK signaling
Zeng et al., Expert Opin Ther Targets 2008 (Cell Transformation, Neoplastic...) : In mammals, RKIP regulates activation of MAPK , NF-kappaB and G protein coupled receptors ( GPCRs )
Ma et al., Liver Int 2009 : Raf kinase inhibitor protein inhibits ERK/MAPK signalling and this inhibition impedes HSC proliferation
Eves et al., Methods Mol Biol 2010 : As demonstrated by immunofluorescence at kinetochores, depletion of Raf Kinase Inhibitory Protein (RKIP) , an inhibitor of Raf/MEK/ERK signaling, causes an increase in MAPK activity that inhibits Aurora B kinase activity
Antoun et al., J Neurosci 2012 (MAP Kinase Signaling System) : Collectively, our data reveal an important role of RKIP in the regulation of MAPK/ERK signaling in the SCN and photic entrainment of the SCN clock
Zeng et al., Cell Signal 2013 (MAP Kinase Signaling System) : Here, we demonstrate that Raf kinase inhibitory protein (RKIP) regulates the activation of MAPK when B-Raf signaling is defective