UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to IL6

IL6 — PIAS1

Pathways - manually collected, often from reviews:

NCI Pathway Database IL6-mediated signaling events: PIAS1 (PIAS1) → IL6/IL6RA/gp130 (dimer)/JAK1/JAK1/LMO4 complex (IL6-IL6R-IL6ST-JAK1-LMO4) (modification, collaborate)
Liu et al., Proc Natl Acad Sci U S A 1998
Evidence: physical interaction
NCI Pathway Database IL6-mediated signaling events: IL6/IL6RA/gp130 (dimer)/JAK1/JAK1/LMO4 complex (IL6-IL6R-IL6ST-JAK1-LMO4) → STAT1/PIAS1 complex (STAT1-PIAS1) (modification, activates)
Liu et al., Proc Natl Acad Sci U S A 1998
Evidence: physical interaction