Steinbusch et al., J Mol Cell Cardiol 2013
(Insulin Resistance) :
In contrast, overexpression of PKD prevented lipid accumulation, but not loss of insulin signaling in HI- and HP-cultured cardiomyocytes
Gehart et al., Communicative & integrative biology 2013
:
Here we discuss two important questions related to this work : How might completion of granule loading be sensed by PKD , and how does Arfaptin-1 specifically regulate insulin granule formation in beta cells ?