Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Sieuwerts et al., Thromb Haemost 2002 (Breast Neoplasms...) : In breast stroma urokinase plasminogen activator (uPA) is predominantly expressed by fibroblasts located in the near vicinity of tumor cells, and fibroblast derived insulin-like growth factor-1 (IGF-1) may be involved in inhibiting the expression of uPA in these fibroblasts
Rosselli et al., Biol Reprod 1992 : Insulin also stimulated uPa and tPa production by prepubertal Sertoli cells, and retinol significantly suppressed uPa production and the ability of FSH to stimulate tPa production by midpubertal Sertoli cells
Politis et al., J Dairy Sci 1996 : Insulin and IGF-I increased synthesis of urokinase plasminogen activator and enhanced proliferation of cultured bovine mammary epithelial cells