Gene interactions and pathways from curated databases and text-mining

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MAPK14 — PSEN1

Text-mined interactions from Literome

Shin et al., Neurosci Lett 1999 (Alzheimer Disease) : Presenilin 1 mediates protein kinase C dependent alpha-secretase derived amyloid precursor protein secretion and mitogen activated protein kinase activation in presenilin 1 transfected human embryonic kidney 293 cell
Mitsuda et al., J Biol Chem 2001 : Conversely, constitutive expression of mitogen activated protein kinase/extracellular signal regulated kinase ( MEK ) results in activation of CREB and increased PS-1 expression that can be blocked by the addition of selective MEK inhibitors