Gene interactions and pathways from curated databases and text-mining

◀ Back to AKT2

AKT2 — PTPN2

Text-mined interactions from Literome

Galic et al., Mol Cell Biol 2005 : Consistent with this, suppression of TCPTP protein levels by RNA interference in PTP1B-/- MEFs resulted in no change in ERK1/2 signaling but caused prolonged Akt activation and Y1162/Y1163 phosphorylation
Brenndörfer et al., Hepatology 2009 : CONCLUSION : This down-regulation of TC-PTP results in an enhancement of epithelial growth factor (EGF) induced signal transduction and increases basal activity of Akt , which is demonstrated to be essential for the maintenance of sufficient viral replication