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CCR7 — TLR5

Text-mined interactions from Literome

Muthuswamy et al., Blood 2010 (Melanoma) : In contrast to the PGE ( 2 ) -matured DCs, DCs matured in the presence of toll-like receptor ( TLR ) ligands and interferons produce high levels of both CCL19 and CCR7 mRNA/protein, but show selectively reduced expression of surface CCR7 , which is compensated after DC removal from the CCL19-rich maturation environment
Hanley et al., PLoS Pathog 2010 (HIV Infections) : Here, we show that ligands for peroxisome proliferator activated receptor gamma ( PPARgamma ) and liver X receptor ( LXR ) prevented proinflammatory cytokine production by DCs and inhibited DC migration in response to the chemokine CCL21 by preventing the TLR induced upregulation of CCR7