Human Gene KLC4 (uc003otr.1)
  Description: Homo sapiens kinesin light chain 4 (KLC4), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr6:43,008,515-43,042,833 Size: 34,319 Total Exon Count: 18 Strand: +


Page IndexSequence and LinksPrimersCTDRNA-Seq ExpressionMicroarray Expression
Other SpeciesmRNA DescriptionsOther NamesGeneReviewsModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6:43,008,515-43,042,833)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSEnsemblExonPrimerGeneNetworkH-INVHGNC
LynxPubMedWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 29.76 RPKM in Liver
Total median expression: 543.54 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK127018 - Homo sapiens cDNA FLJ45074 fis, clone BRAWH3027440, highly similar to Probable kinesin light chain 3.
JD505268 - Sequence 486292 from Patent EP1572962.
AK297433 - Homo sapiens cDNA FLJ58264 complete cds, highly similar to Kinesin light chain 4.
AK056393 - Homo sapiens cDNA FLJ31831 fis, clone NT2RP6000123, highly similar to Kinesin light chain 4.
BC012357 - Homo sapiens kinesin light chain 4, mRNA (cDNA clone IMAGE:4654235), complete cds.
BC080637 - Homo sapiens kinesin light chain 4, mRNA (cDNA clone MGC:99549 IMAGE:6573021), complete cds.
BC103727 - Homo sapiens kinesin light chain 4, mRNA (cDNA clone MGC:111777 IMAGE:6157949), complete cds.
AK094102 - Homo sapiens cDNA FLJ36783 fis, clone ADRGL2001830, highly similar to Kinesin light chain 4.
AK055293 - Homo sapiens cDNA FLJ30731 fis, clone FEBRA2000105, highly similar to Kinesin light chain 4.
BX640717 - Homo sapiens mRNA; cDNA DKFZp686J01192 (from clone DKFZp686J01192).
AK127894 - Homo sapiens cDNA FLJ46000 fis, clone SMINT2010753, highly similar to Probable kinesin light chain 3.
DQ895432 - Synthetic construct Homo sapiens clone IMAGE:100009892; FLH184347.01L; RZPDo839E12143D kinesin light chain 4 (KLC4) gene, encodes complete protein.
DQ892231 - Synthetic construct clone IMAGE:100004861; FLH184351.01X; RZPDo839E12144D kinesin light chain 4 (KLC4) gene, encodes complete protein.
EU831841 - Synthetic construct Homo sapiens clone HAIB:100066870; DKFZo004B0722 kinesin light chain 4 protein (KLC4) gene, encodes complete protein.
EU831763 - Synthetic construct Homo sapiens clone HAIB:100066792; DKFZo008B0721 kinesin light chain 4 protein (KLC4) gene, encodes complete protein.
AL162078 - Homo sapiens mRNA; cDNA DKFZp761H229 (from clone DKFZp761H229); partial cds.

-  Other Names for This Gene
  Alternate Gene Symbols: AK127018
UCSC ID: uc003otr.1
RefSeq Accession: NM_201521

-  GeneReviews for This Gene
  GeneReviews article(s) related to gene KLC4:
hsp (Hereditary Spastic Paraplegia Overview)

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: AK127018.1
exon count: 18CDS single in 3' UTR: no RNA size: 3604
ORF size: 0CDS single in intron: no Alignment % ID: 99.83
txCdsPredict score: 491.50frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.