Human Gene TCTN3 (ENST00000614499.5) from GENCODE V44
Description: tectonic family member 3 (from HGNC TCTN3) RefSeq Summary (NM_015631): This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]. Gencode Transcript: ENST00000614499.5 Gencode Gene: ENSG00000119977.22 Transcript (Including UTRs) Position: hg38 chr10:95,663,414-95,693,989 Size: 30,576 Total Exon Count: 14 Strand: - Coding Region Position: hg38 chr10:95,664,067-95,693,953 Size: 29,887 Coding Exon Count: 14
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.