Human Gene JMJD7 (ENST00000397299.9) from GENCODE V44
Description: Homo sapiens jumonji domain containing 7 (JMJD7), mRNA. (from RefSeq NM_001114632) RefSeq Summary (NM_001114632): This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000397299.9 Gencode Gene: ENSG00000243789.11 Transcript (Including UTRs) Position: hg38 chr15:41,828,092-41,837,581 Size: 9,490 Total Exon Count: 8 Strand: + Coding Region Position: hg38 chr15:41,828,125-41,837,156 Size: 9,032 Coding Exon Count: 8
ID:JMJD7_HUMAN DESCRIPTION: RecName: Full=JmjC domain-containing protein 7; AltName: Full=Jumonji domain-containing protein 7; SIMILARITY: Contains 1 JmjC domain. CAUTION: This sequence was first thought to be an alternatively spliced isoform of PLA2G4B. It is derived from JMJD7 which is located upstream of PLA2G4B. Most tissues also express read- through transcripts from JMJD7 into the downstream PLA2G4B gene, some of which may encode fusion proteins combining the N-terminus of this protein with PLA2G4B protein.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P0C870
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
