Human Gene CTRB1 (ENST00000361017.9) from GENCODE V44
Description: Homo sapiens chymotrypsinogen B1 (CTRB1), transcript variant 1, mRNA. (from RefSeq NM_001906) RefSeq Summary (NM_001906): This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This gene is located adjacent to a related chymotrypsinogen gene. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Jul 2016]. Gencode Transcript: ENST00000361017.9 Gencode Gene: ENSG00000168925.12 Transcript (Including UTRs) Position: hg38 chr16:75,218,988-75,224,924 Size: 5,937 Total Exon Count: 7 Strand: + Coding Region Position: hg38 chr16:75,219,008-75,224,866 Size: 5,859 Coding Exon Count: 7
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P17538
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
