Human Gene SLC35F6 (ENST00000344420.10) from GENCODE V44
Description: Homo sapiens solute carrier family 35 member F6 (SLC35F6), mRNA. (from RefSeq NM_017877)
Gencode Transcript: ENST00000344420.10
Gencode Gene: ENSG00000213699.9
Transcript (Including UTRs)
Position: hg38 chr2:26,764,284-26,781,231 Size: 16,948 Total Exon Count: 6 Strand: +
Coding Region
Position: hg38 chr2:26,764,350-26,778,511 Size: 14,162 Coding Exon Count: 6
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CB018_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein C2orf18; Flags: Precursor;
SUBCELLULAR LOCATION: Lysosome membrane; Multi-pass membrane protein.SIMILARITY: Contains 1 EamA domain.
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR009262 - DUF914_euk
IPR012404 - UCP036436
Pfam Domains: PF06027 - Solute carrier family 35
ModBase Predicted Comparative 3D Structure on Q8N357
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK000562 - Homo sapiens cDNA FLJ20555 fis, clone KAT11822.JD462010 - Sequence 443034 from Patent EP1572962.BC028081 - Homo sapiens chromosome 2 open reading frame 18, mRNA (cDNA clone MGC:39919 IMAGE:5216816), complete cds.BC035519 - Homo sapiens chromosome 2 open reading frame 18, mRNA (cDNA clone IMAGE:5225493).BX647807 - Homo sapiens mRNA; cDNA DKFZp686J0896 (from clone DKFZp686J0896).AK075164 - Homo sapiens cDNA FLJ90683 fis, clone PLACE1005927.AK296996 - Homo sapiens cDNA FLJ55094 complete cds.BC011013 - Homo sapiens centromere protein A, mRNA (cDNA clone IMAGE:4286607), **** WARNING: chimeric clone ****.AK299598 - Homo sapiens cDNA FLJ59967 complete cds.AY358820 - Homo sapiens clone DNA125164 AWTK3047 (UNQ3047) mRNA, complete cds.AK222929 - Homo sapiens mRNA for chromosome 2 open reading frame 18 variant, clone: HRC08074.BX648017 - Homo sapiens mRNA; cDNA DKFZp686N0996 (from clone DKFZp686N0996).CU688388 - Synthetic construct Homo sapiens gateway clone IMAGE:100019119 5' read C2orf18 mRNA.KJ894108 - Synthetic construct Homo sapiens clone ccsbBroadEn_03502 C2orf18 gene, encodes complete protein.CR457243 - Homo sapiens full open reading frame cDNA clone RZPDo834E0912D for gene C2orf18, chromosome 2 open reading frame 18; complete cds, incl. stopcodon.JD231109 - Sequence 212133 from Patent EP1572962.JD179385 - Sequence 160409 from Patent EP1572962.JD393637 - Sequence 374661 from Patent EP1572962.JD079869 - Sequence 60893 from Patent EP1572962.JD124379 - Sequence 105403 from Patent EP1572962.BC005887 - Homo sapiens chromosome 2 open reading frame 18, mRNA (cDNA clone IMAGE:3604869), partial cds.JD496990 - Sequence 478014 from Patent EP1572962.JD489003 - Sequence 470027 from Patent EP1572962.JD499601 - Sequence 480625 from Patent EP1572962.JD225370 - Sequence 206394 from Patent EP1572962.BC016389 - Homo sapiens chromosome 2 open reading frame 18, mRNA (cDNA clone IMAGE:3860139).JD311850 - Sequence 292874 from Patent EP1572962.JD081662 - Sequence 62686 from Patent EP1572962.JD091431 - Sequence 72455 from Patent EP1572962.JD103313 - Sequence 84337 from Patent EP1572962.JD097655 - Sequence 78679 from Patent EP1572962.JD425301 - Sequence 406325 from Patent EP1572962.JD039938 - Sequence 20962 from Patent EP1572962.JD398552 - Sequence 379576 from Patent EP1572962.AK025889 - Homo sapiens cDNA: FLJ22236 fis, clone HRC02042.JD082317 - Sequence 63341 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: C2orf18, CB018_HUMAN, D6W543, ENST00000344420.1, ENST00000344420.2, ENST00000344420.3, ENST00000344420.4, ENST00000344420.5, ENST00000344420.6, ENST00000344420.7, ENST00000344420.8, ENST00000344420.9, NM_017877, Q53GK2, Q8N357, Q8NBX6, Q9NWX0, uc002rhp.1, uc002rhp.2, uc002rhp.3, UNQ3047/PRO9863UCSC ID: ENST00000344420.10RefSeq Accession: NM_017877
Protein: Q8N357
(aka CB018_HUMAN)
CCDS: CCDS1728.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.