Human Gene DHX35 (ENST00000252011.8) from GENCODE V44
Description: Homo sapiens DEAH-box helicase 35 (DHX35), transcript variant 3, non-coding RNA. (from RefSeq NR_033905) RefSeq Summary (NM_021931): DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of this gene product which is a member of this family, has not been determined. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2010]. Gencode Transcript: ENST00000252011.8 Gencode Gene: ENSG00000101452.15 Transcript (Including UTRs) Position: hg38 chr20:38,962,344-39,039,721 Size: 77,378 Total Exon Count: 22 Strand: + Coding Region Position: hg38 chr20:38,962,368-39,038,543 Size: 76,176 Coding Exon Count: 22
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H5Z1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
