Human Gene TAFA5 (ENST00000358295.9) from GENCODE V44
Description: Homo sapiens TAFA chemokine like family member 5 (TAFA5), transcript variant 2, mRNA. (from RefSeq NM_015381) RefSeq Summary (NM_015381): This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells. [provided by RefSeq, Sep 2013]. Gencode Transcript: ENST00000358295.9 Gencode Gene: ENSG00000219438.9 Transcript (Including UTRs) Position: hg38 chr22:48,576,306-48,751,932 Size: 175,627 Total Exon Count: 4 Strand: + Coding Region Position: hg38 chr22:48,576,481-48,749,847 Size: 173,367 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q7Z5A7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.