Human Gene NICN1 (ENST00000273598.8) from GENCODE V44
Description: Homo sapiens nicolin 1 (NICN1), mRNA. (from RefSeq NM_032316) RefSeq Summary (NM_032316): This protein encoded by this gene localizes to the nucleus and is expressed in numerous tissues including brain, testis, liver, and kidney. This refseq contains genomic sequence in its 3' UTR which is not supported by experimental evidence. Computer predictions indicate that this region of the 3' UTR contains hairpin-forming self-complementary sequence which is possibly excised after transcription. This gene has a pseudogene on chromosome X. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000273598.8 Gencode Gene: ENSG00000145029.15 Transcript (Including UTRs) Position: hg38 chr3:49,422,333-49,429,324 Size: 6,992 Total Exon Count: 6 Strand: - Coding Region Position: hg38 chr3:49,424,833-49,429,239 Size: 4,407 Coding Exon Count: 6
ID:NICN1_HUMAN DESCRIPTION: RecName: Full=Nicolin-1; AltName: Full=NPCEDRG; AltName: Full=Tubulin polyglutamylase complex subunit 5; Short=PGs5; SUBUNIT: Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1 (By similarity). SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: High expression level is found in brain, testis, liver and kidney. Weak expression in spleen, leukocytes, small intestine and colon.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q9BSH3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
