Human Gene TSPAN5 (ENST00000305798.8) from GENCODE V44
Description: Homo sapiens tetraspanin 5 (TSPAN5), mRNA. (from RefSeq NM_005723) RefSeq Summary (NM_005723): The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000305798.8 Gencode Gene: ENSG00000168785.8 Transcript (Including UTRs) Position: hg38 chr4:98,470,367-98,658,611 Size: 188,245 Total Exon Count: 8 Strand: - Coding Region Position: hg38 chr4:98,472,522-98,658,226 Size: 185,705 Coding Exon Count: 8
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P62079
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0045747 positive regulation of Notch signaling pathway GO:0051604 protein maturation GO:0072659 protein localization to plasma membrane
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