Human Gene IL9 (ENST00000274520.2) from GENCODE V44
Description: Homo sapiens interleukin 9 (IL9), mRNA. (from RefSeq NM_000590) RefSeq Summary (NM_000590): The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000274520.2 Gencode Gene: ENSG00000145839.2 Transcript (Including UTRs) Position: hg38 chr5:135,892,246-135,895,841 Size: 3,596 Total Exon Count: 5 Strand: - Coding Region Position: hg38 chr5:135,892,391-135,895,816 Size: 3,426 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P15248
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
