Human Gene TAGAP (ENST00000367066.8) from GENCODE V44
Description: Homo sapiens T cell activation RhoGTPase activating protein (TAGAP), transcript variant 2, mRNA. (from RefSeq NM_054114) RefSeq Summary (NM_054114): This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]. Gencode Transcript: ENST00000367066.8 Gencode Gene: ENSG00000164691.18 Transcript (Including UTRs) Position: hg38 chr6:159,034,481-159,044,991 Size: 10,511 Total Exon Count: 10 Strand: - Coding Region Position: hg38 chr6:159,035,827-159,044,146 Size: 8,320 Coding Exon Count: 9
ID:TAGAP_HUMAN DESCRIPTION: RecName: Full=T-cell activation Rho GTPase-activating protein; AltName: Full=T-cell activation GTPase-activating protein; FUNCTION: May function as a GTPase-activating protein and may play important roles during T-cell activation. SIMILARITY: Contains 1 Rho-GAP domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N103
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007165 signal transduction GO:0043547 positive regulation of GTPase activity GO:0051056 regulation of small GTPase mediated signal transduction
US Server
