Human Gene HIBADH (ENST00000265395.7) from GENCODE V44
Description: Homo sapiens 3-hydroxyisobutyrate dehydrogenase (HIBADH), mRNA; nuclear gene for mitochondrial product. (from RefSeq NM_152740) RefSeq Summary (NM_152740): This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde. [provided by RefSeq, Nov 2011]. Gencode Transcript: ENST00000265395.7 Gencode Gene: ENSG00000106049.9 Transcript (Including UTRs) Position: hg38 chr7:27,525,442-27,662,883 Size: 137,442 Total Exon Count: 8 Strand: - Coding Region Position: hg38 chr7:27,526,214-27,662,788 Size: 136,575 Coding Exon Count: 8
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P31937
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
