Human Gene COA8 (ENST00000409074.8) from GENCODE V44
Description: Homo sapiens cytochrome c oxidase assembly factor 8 (COA8), transcript variant 6, non-coding RNA. (from RefSeq NR_126431) RefSeq Summary (NM_001302653): This gene encodes a protein that localizes to the mitochondria, where it stimulates the release of cytochrome c, thereby promoting programmed cell death. Mutations in this gene have been found in individuals with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]. Gencode Transcript: ENST00000409074.8 Gencode Gene: ENSG00000256053.9 Transcript (Including UTRs) Position: hg38 chr14:103,562,960-103,590,896 Size: 27,937 Total Exon Count: 5 Strand: + Coding Region Position: hg38 chr14:103,563,002-103,590,286 Size: 27,285 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
