Human Gene C3orf33 (ENST00000534941.2) from GENCODE V44
Description: Homo sapiens chromosome 3 open reading frame 33 (C3orf33), transcript variant 2, mRNA. (from RefSeq NM_173657)
Gencode Transcript: ENST00000534941.2
Gencode Gene: ENSG00000174928.16
Transcript (Including UTRs)
Position: hg38 chr3:155,762,618-155,806,272 Size: 43,655 Total Exon Count: 5 Strand: -
Coding Region
Position: hg38 chr3:155,763,517-155,802,576 Size: 39,060 Coding Exon Count: 4
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CC033_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C3orf33;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).SEQUENCE CAUTION: Sequence=AAO06952.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR006021 - Staphylococcal_nuclease
ModBase Predicted Comparative 3D Structure on Q6P1S2
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Biological Process: GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
GO:0070373 negative regulation of ERK1 and ERK2 cascade
Cellular Component: GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0016020 membrane
GO:0016021 integral component of membrane
Descriptions from all associated GenBank mRNAs
AK055701 - Homo sapiens cDNA FLJ31139 fis, clone IMR322001185.AF115515 - Homo sapiens MSTP052 (MST052) mRNA, complete cds.BC064898 - Homo sapiens chromosome 3 open reading frame 33, mRNA (cDNA clone MGC:70365 IMAGE:6008321), complete cds.AL832165 - Homo sapiens mRNA; cDNA DKFZp686E11158 (from clone DKFZp686E11158).BC042198 - Homo sapiens chromosome 3 open reading frame 33, mRNA (cDNA clone IMAGE:5109794), partial cds.JD553415 - Sequence 534439 from Patent EP1572962.JD364062 - Sequence 345086 from Patent EP1572962.JD345280 - Sequence 326304 from Patent EP1572962.JD046292 - Sequence 27316 from Patent EP1572962.JD069849 - Sequence 50873 from Patent EP1572962.JD532441 - Sequence 513465 from Patent EP1572962.AK289890 - Homo sapiens cDNA FLJ75973 complete cds.JD262304 - Sequence 243328 from Patent EP1572962.JD087200 - Sequence 68224 from Patent EP1572962.JD513463 - Sequence 494487 from Patent EP1572962.JD491988 - Sequence 473012 from Patent EP1572962.JD295678 - Sequence 276702 from Patent EP1572962.JD262345 - Sequence 243369 from Patent EP1572962.JD154222 - Sequence 135246 from Patent EP1572962.JD198770 - Sequence 179794 from Patent EP1572962.JD388563 - Sequence 369587 from Patent EP1572962.JD152958 - Sequence 133982 from Patent EP1572962.JD198312 - Sequence 179336 from Patent EP1572962.JD140585 - Sequence 121609 from Patent EP1572962.JD388562 - Sequence 369586 from Patent EP1572962.JD491986 - Sequence 473010 from Patent EP1572962.JD523618 - Sequence 504642 from Patent EP1572962.JD281398 - Sequence 262422 from Patent EP1572962.JD160748 - Sequence 141772 from Patent EP1572962.JD281397 - Sequence 262421 from Patent EP1572962.JD152957 - Sequence 133981 from Patent EP1572962.JD557917 - Sequence 538941 from Patent EP1572962.JD326398 - Sequence 307422 from Patent EP1572962.JD480449 - Sequence 461473 from Patent EP1572962.JD108077 - Sequence 89101 from Patent EP1572962.JD108078 - Sequence 89102 from Patent EP1572962.JD413749 - Sequence 394773 from Patent EP1572962.JD213084 - Sequence 194108 from Patent EP1572962.JD542922 - Sequence 523946 from Patent EP1572962.JD165234 - Sequence 146258 from Patent EP1572962.JD262081 - Sequence 243105 from Patent EP1572962.JD087078 - Sequence 68102 from Patent EP1572962.JD448871 - Sequence 429895 from Patent EP1572962.JD440612 - Sequence 421636 from Patent EP1572962.JD558173 - Sequence 539197 from Patent EP1572962.JD236269 - Sequence 217293 from Patent EP1572962.KJ905070 - Synthetic construct Homo sapiens clone ccsbBroadEn_14464 C3orf33 gene, encodes complete protein.
Other Names for This Gene
Alternate Gene Symbols: A8K1H5, CC033_HUMAN, ENST00000534941.1, MSTP052, NM_173657, Q6P1S2, Q86YE6, Q8IXA7, uc062pfq.1UCSC ID: ENST00000534941.2RefSeq Accession: NM_001308229
Protein: Q6P1S2
(aka CC033_HUMAN)
CCDS: CCDS54659.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.