Human Gene MT-TF (ENST00000387314.1) from GENCODE V44
  Description: mitochondrially encoded tRNA phenylalanine (from HGNC MT-TF)
Gencode Transcript: ENST00000387314.1
Gencode Gene: ENSG00000210049.1
Transcript (Including UTRs)
   Position: hg38 chrM:577-647 Size: 71 Total Exon Count: 1 Strand: +


Page IndexSequence and LinksPrimersMalaCardsRNA-Seq ExpressionMicroarray Expression
Other SpeciesmRNA DescriptionsOther NamesGeneReviewsMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrM:577-647)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaEnsembl
ExonPrimerGencodeHGNCMalacardsPubMed

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: MT-TF
Diseases sorted by gene-association score: myoclonic epilepsy associated with ragged-red fibers* (375), mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes* (306), melas, mt-tf-related* (100), mitochondrial disorders* (22)
* = Manually curated disease association

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.90 RPKM in Brain - Anterior cingulate cortex (BA24)
Total median expression: 6.89 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  LP895143 - Sequence 7 from Patent EP3253886.
DQ598675 - Homo sapiens piRNA piR-36741, complete sequence.
JB137817 - Sequence 6 from Patent WO2012164058.
MK671731 - Homo sapiens i-tRF-PheGAA tRNA-derived RNA fragment, complete sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: DQ598675, uc064xos.1
UCSC ID: ENST00000387314.1
Representative RNA: DQ598675

-  GeneReviews for This Gene
  GeneReviews article(s) related to gene MT-TF:
melas (MELAS)
merrf (MERRF)
mt-overview (Primary Mitochondrial Disorders Overview)

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.