Mouse Gene Fgf17 (ENSMUST00000022697.6) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus fibroblast growth factor 17 (Fgf17), transcript variant 1, mRNA. (from RefSeq NM_008004)
Gencode Transcript: ENSMUST00000022697.6
Gencode Gene: ENSMUSG00000022101.6
Transcript (Including UTRs)
   Position: mm10 chr14:70,636,203-70,642,268 Size: 6,066 Total Exon Count: 5 Strand: -
Coding Region
   Position: mm10 chr14:70,636,730-70,641,757 Size: 5,028 Coding Exon Count: 5 

Page IndexSequence and LinksCTDRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:70,636,203-70,642,268)mRNA (may differ from genome)Protein (216 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedStanford SOURCEUniProtKBWikipedia

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -200.90511-0.393 Picture PostScript Text
3' UTR -175.30527-0.333 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR008996 - Cytokine_IL1-like
IPR002348 - IL1_HBGF

Pfam Domains:
PF00167 - Fibroblast growth factor

SCOP Domains:
50353 - Cytokine
50405 - Actin-crosslinking proteins

ModBase Predicted Comparative 3D Structure on Q0VF19
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
 RGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005104 fibroblast growth factor receptor binding
GO:0005105 type 1 fibroblast growth factor receptor binding
GO:0005111 type 2 fibroblast growth factor receptor binding
GO:0008083 growth factor activity

Biological Process:
GO:0008284 positive regulation of cell proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010469 regulation of receptor activity

Cellular Component:
GO:0005576 extracellular region


-  Descriptions from all associated GenBank mRNAs
  LF200068 - JP 2014500723-A/7571: Polycomb-Associated Non-Coding RNAs.
AK082858 - Mus musculus ES cells cDNA, RIKEN full-length enriched library, clone:C330044C05 product:fibroblast growth factor 17, full insert sequence.
AK077555 - Mus musculus 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730446E06 product:fibroblast growth factor 17, full insert sequence.
LF241964 - JP 2014500723-A/49467: Polycomb-Associated Non-Coding RNAs.
LF241965 - JP 2014500723-A/49468: Polycomb-Associated Non-Coding RNAs.
BC119033 - Mus musculus fibroblast growth factor 17, mRNA (cDNA clone MGC:155349 IMAGE:8733782), complete cds.
BC144776 - Mus musculus fibroblast growth factor 17, mRNA (cDNA clone MGC:178332 IMAGE:9053324), complete cds.
AB009250 - Mus musculus mRNA for FGF-17, complete cds.
LF241966 - JP 2014500723-A/49469: Polycomb-Associated Non-Coding RNAs.
LF241969 - JP 2014500723-A/49472: Polycomb-Associated Non-Coding RNAs.
LF241970 - JP 2014500723-A/49473: Polycomb-Associated Non-Coding RNAs.
MA435645 - JP 2018138019-A/7571: Polycomb-Associated Non-Coding RNAs.
MA477541 - JP 2018138019-A/49467: Polycomb-Associated Non-Coding RNAs.
MA477542 - JP 2018138019-A/49468: Polycomb-Associated Non-Coding RNAs.
MA477543 - JP 2018138019-A/49469: Polycomb-Associated Non-Coding RNAs.
MA477546 - JP 2018138019-A/49472: Polycomb-Associated Non-Coding RNAs.
MA477547 - JP 2018138019-A/49473: Polycomb-Associated Non-Coding RNAs.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
mmu04010 - MAPK signaling pathway
mmu04810 - Regulation of actin cytoskeleton
mmu05200 - Pathways in cancer
mmu05218 - Melanoma

-  Other Names for This Gene
  Alternate Gene Symbols: mCG_16192, NM_008004, Q0VF19, Q0VF19_MOUSE, uc007uos.1, uc007uos.2
UCSC ID: uc007uos.2
RefSeq Accession: NM_008004
Protein: Q0VF19 CCDS: CCDS27260.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.