Mouse Gene Runx1 (ENSMUST00000168195.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus runt related transcription factor 1 (Runx1), transcript variant 3, mRNA. (from RefSeq NM_001111023)
Gencode Transcript: ENSMUST00000168195.7
Gencode Gene: ENSMUSG00000022952.17
Transcript (Including UTRs)
Position: mm10 chr16:92,605,398-92,696,125 Size: 90,728 Total Exon Count: 6 Strand: -
Position: mm10 chr16:92,605,655-92,695,753 Size: 90,099 Coding Exon Count: 6
Data last updated at UCSC: 2019-09-19
Sequence and Links to Tools and Databases
Comparative Toxicogenomics Database (CTD)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR013524 - AML1/Runt_N
IPR000040 - AML1_Runt
IPR008967 - p53-like_TF_DNA-bd
IPR012346 - p53/RUNT-type_TF_DNA-bd
IPR013711 - RunxI
IPR016554 - TF_Runt-rel_RUNX
Pfam Domains: PF00853 - Runt domain
PF08504 - Runx inhibition domain
SCOP Domains: 49417 - p53-like transcription factors
ModBase Predicted Comparative 3D Structure on G3UWD2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005524 ATP binding
Biological Process: GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component: GO:0005634 nucleus
Descriptions from all associated GenBank mRNAs
AK145098 - Mus musculus mammary gland RCB-0526 Jyg-MC(A) cDNA, RIKEN full-length enriched library, clone:G830041K20 product:runt related transcription factor 1, full insert sequence. AK137493 - Mus musculus adult male bone cDNA, RIKEN full-length enriched library, clone:9830114D24 product:runt related transcription factor 1, full insert sequence. AK165307 - Mus musculus 6 days neonate spleen cDNA, RIKEN full-length enriched library, clone:F430011O05 product:unclassifiable, full insert sequence. AK051758 - Mus musculus 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched library, clone:D130073O22 product:runt related transcription factor 1, full insert sequence. D26532 - Mus musculus PEBP2aB2 mRNA for transcription factor, complete cds. BC069929 - Mus musculus runt related transcription factor 1, mRNA (cDNA clone MGC:78210 IMAGE:4008335), complete cds. D13802 - Mus musculus mRNA for PEBP2aB protein, complete cds. AK153274 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830130P15 product:runt related transcription factor 1, full insert sequence. AK155262 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630212H16 product:runt related transcription factor 1, full insert sequence. X97306 - M.musculus mRNA for CBFA2 protein. AB352489 - Mus musculus non-coding RNA, oocyte_piRNA3305, complete sequence.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: G3UWD2, G3UWD2_MOUSE, mCG_13559, NM_001111023, uc007zzi.1, uc007zzi.2, uc007zzi.3, uc007zzi.4 UCSC ID: uc007zzi.4 RefSeq Accession: NM_001111023
G3UWD2 CCDS: CCDS49916.1, CCDS49917.1
Gene Model Information
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.