S. cerevisiae Gene RPA14 (YDR156W)
  Description: RNA polymerase I subunit A14
Transcript (Including UTRs)
   Position: sacCer3 chrIV:769,525-769,938 Size: 414 Total Exon Count: 1 Strand: +
Coding Region
   Position: sacCer3 chrIV:769,525-769,938 Size: 414 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2011-08-29

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrIV:769,525-769,938)mRNAProtein (137 aa)
Gene SorterGenome BrowserOther Species FASTASGDUniProtKB

-  Comments and Description Text from UniProtKB
  ID: RPA14_YEAST
DESCRIPTION: RecName: Full=DNA-directed RNA polymerase I subunit RPA14; Short=A14; AltName: Full=DNA-directed RNA polymerase I 14 kDa polypeptide;
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. A14 seems to play a role in the stability of subunits ABC23 and A43. In vitro, the A14-A43 subcomplex binds single-stranded RNA.
SUBUNIT: Component of the RNA polymerase I (Pol I) complex consisting of 14 subunits. Part of a Pol I subcomplex consisting of the subunits A14 and A43. Interacts with RPA43.
SUBCELLULAR LOCATION: Nucleus, nucleolus.
PTM: The N-terminus is blocked.
MISCELLANEOUS: Present with 3100 molecules/cell in log phase SD medium.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR013239 - RNA_polI_RPA14

Pfam Domains:
PF08203 - Yeast RNA polymerase I subunit RPA14

Protein Data Bank (PDB) 3-D Structure
MuPIT help

2RF4
- X-ray


ModBase Predicted Comparative 3D Structure on P50106
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanMouseRatZebrafishD. melanogasterC. elegans
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0001054 RNA polymerase I activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding

Biological Process:
GO:0006360 transcription from RNA polymerase I promoter
GO:0042254 ribosome biogenesis
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter

Cellular Component:
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005736 DNA-directed RNA polymerase I complex


-  Descriptions from all associated GenBank mRNAs
 

-  Other Names for This Gene
  UCSC ID: YDR156W
Protein: P50106 (aka RPA14_YEAST)

-  SGD Genes Methods, Credits, and Data Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.