S. cerevisiae Gene RPA14 (YDR156W)
  Description: RNA polymerase I subunit A14
Transcript (Including UTRs)
   Position: sacCer3 chrIV:769,525-769,938 Size: 414 Total Exon Count: 1 Strand: +
Coding Region
   Position: sacCer3 chrIV:769,525-769,938 Size: 414 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2011-08-29

-  Sequence and Links to Tools and Databases
Genomic Sequence (chrIV:769,525-769,938)mRNAProtein (137 aa)
Gene SorterGenome BrowserOther Species FASTASGDUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=DNA-directed RNA polymerase I subunit RPA14; Short=A14; AltName: Full=DNA-directed RNA polymerase I 14 kDa polypeptide;
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. A14 seems to play a role in the stability of subunits ABC23 and A43. In vitro, the A14-A43 subcomplex binds single-stranded RNA.
SUBUNIT: Component of the RNA polymerase I (Pol I) complex consisting of 14 subunits. Part of a Pol I subcomplex consisting of the subunits A14 and A43. Interacts with RPA43.
SUBCELLULAR LOCATION: Nucleus, nucleolus.
PTM: The N-terminus is blocked.
MISCELLANEOUS: Present with 3100 molecules/cell in log phase SD medium.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR013239 - RNA_polI_RPA14

Pfam Domains:
PF08203 - Yeast RNA polymerase I subunit RPA14

Protein Data Bank (PDB) 3-D Structure
MuPIT help

- X-ray

ModBase Predicted Comparative 3D Structure on P50106
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanMouseRatZebrafishD. melanogasterC. elegans
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0001054 RNA polymerase I activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding

Biological Process:
GO:0006360 transcription from RNA polymerase I promoter
GO:0042254 ribosome biogenesis
GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter

Cellular Component:
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005736 DNA-directed RNA polymerase I complex

-  Descriptions from all associated GenBank mRNAs

-  Other Names for This Gene
Protein: P50106 (aka RPA14_YEAST)

-  SGD Genes Methods, Credits, and Data Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.