S. cerevisiae Gene RPA14 (YDR156W)
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Sequence and Links to Tools and Databases
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Comments and Description Text from UniProtKB
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ID: RPA14_YEAST
DESCRIPTION: RecName: Full=DNA-directed RNA polymerase I subunit RPA14; Short=A14; AltName: Full=DNA-directed RNA polymerase I 14 kDa polypeptide;
FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. A14 seems to play a role in the stability of subunits ABC23 and A43. In vitro, the A14-A43 subcomplex binds single-stranded RNA. SUBUNIT: Component of the RNA polymerase I (Pol I) complex consisting of 14 subunits. Part of a Pol I subcomplex consisting of the subunits A14 and A43. Interacts with RPA43. SUBCELLULAR LOCATION: Nucleus, nucleolus. PTM: The N-terminus is blocked. MISCELLANEOUS: Present with 3100 molecules/cell in log phase SD medium.
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Primer design for this transcript
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Protein Domain and Structure Information
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InterPro Domains: Graphical view of domain structure IPR013239 - RNA_polI_RPA14
Pfam Domains: PF08203 - Yeast RNA polymerase I subunit RPA14
Protein Data Bank (PDB) 3-D Structure
ModBase Predicted Comparative 3D Structure on P50106
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
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Orthologous Genes in Other Species
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Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Human | Mouse | Rat | Zebrafish | D. melanogaster | C. elegans |
No ortholog | No ortholog | No ortholog | No ortholog | No ortholog | No ortholog |
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Gene Ontology (GO) Annotations with Structured Vocabulary
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Descriptions from all associated GenBank mRNAs
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Other Names for This Gene
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UCSC ID: YDR156W Protein: P50106
(aka RPA14_YEAST)
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SGD Genes Methods, Credits, and Data Use Restrictions
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Click here
for details on how this gene model was made and data restrictions if any.
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