Human Gene PTPN11 (ENST00000351677.7) from GENCODE V43
  Description: Homo sapiens protein tyrosine phosphatase non-receptor type 11 (PTPN11), transcript variant 1, mRNA. (from RefSeq NM_002834)
RefSeq Summary (NM_002834): The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.
Gencode Transcript: ENST00000351677.7
Gencode Gene: ENSG00000179295.19
Transcript (Including UTRs)
   Position: hg38 chr12:112,418,947-112,509,918 Size: 90,972 Total Exon Count: 16 Strand: +
Coding Region
   Position: hg38 chr12:112,419,112-112,504,764 Size: 85,653 Coding Exon Count: 15 

Page IndexSequence and LinksUniProtKB CommentsPrimersMalaCardsCTD
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsPathwaysOther NamesGeneReviewsMethods
Data last updated at UCSC: 2023-02-17 13:02:02

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:112,418,947-112,509,918)mRNA (may differ from genome)Protein (593 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSCGAPEnsemblEntrez GeneExonPrimerGencode
GeneCardsHGNCHPRDLynxMGIneXtProt
OMIMPubMedReactomeUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: PTN11_HUMAN
DESCRIPTION: RecName: Full=Tyrosine-protein phosphatase non-receptor type 11; EC=3.1.3.48; AltName: Full=Protein-tyrosine phosphatase 1D; Short=PTP-1D; AltName: Full=Protein-tyrosine phosphatase 2C; Short=PTP-2C; AltName: Full=SH-PTP2; Short=SHP-2; Short=Shp2; AltName: Full=SH-PTP3;
FUNCTION: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
SUBUNIT: Interacts with phosphorylated LIME1 and BCAR3. Interacts with SHB and INPP5D/SHIP1 (By similarity). Interacts with MILR1 (tyrosine-phosphorylated). Interacts with FLT1 (tyrosine- phosphorylated), FLT3 (tyrosine-phosphorylated), FLT4 (tyrosine- phosphorylated), KIT and GRB2. Interacts with PDGFRA (tyrosine phosphorylated). Interacts (via SH2 domain) with TEK/TIE2 (tyrosine phosphorylated) (By similarity). Interacts with PTPNS1 and CD84. Interacts with phosphorylated SIT1 and MPZL1. Interacts with FCRL3, FCRL4, FCRL6 and ANKHD1. Interacts with KIR2DL1; the interaction is enhanced by ARRB2. Interacts with GAB2. Interacts with TERT; the interaction retains TERT in the nucleus. Interacts with PECAM1 and FER. Interacts with EPHA2 (activated); participates in PTK2/FAK1 dephosphorylation in EPHA2 downstream signaling. Interacts with ROS1; mediates PTPN11 phosphorylation. Interacts with PDGFRB (tyrosine phosphorylated); this interaction increases the PTPN11 phosphatase activity.
INTERACTION: Q13480:GAB1; NbExp=3; IntAct=EBI-297779, EBI-517684; P62993:GRB2; NbExp=6; IntAct=EBI-297779, EBI-401755; O95297:MPZL1; NbExp=2; IntAct=EBI-297779, EBI-963338;
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Widely expressed, with highest levels in heart, brain, and skeletal muscle.
DOMAIN: The SH2 domains repress phosphatase activity. Binding of these domains to phosphotyrosine-containing proteins relieves this auto-inhibition, possibly by inducing a conformational change in the enzyme.
PTM: Phosphorylated on Tyr-546 and Tyr-584 upon receptor protein tyrosine kinase activation; which creates a binding site for GRB2 and other SH2-containing proteins. Phosphorylated upon activation of the receptor-type kinase FLT3. Phosphorylated upon activation of the receptor-type kinase PDGFRA (By similarity). Phosphorylated by activated PDGFRB.
DISEASE: Defects in PTPN11 are the cause of LEOPARD syndrome type 1 (LEOPARD1) [MIM:151100]. It is an autosomal dominant disorder allelic with Noonan syndrome. The acronym LEOPARD stands for lentigines, electrocardiographic conduction abnormalities, ocular hypertelorism, pulmonic stenosis, abnormalities of genitalia, retardation of growth, and deafness.
DISEASE: Defects in PTPN11 are the cause of Noonan syndrome type 1 (NS1) [MIM:163950]. Noonan syndrome (NS) is a disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. Some patients with Noonan syndrome type 1 develop multiple giant cell lesions of the jaw or other bony or soft tissues, which are classified as pigmented villomoduolar synovitis (PVNS) when occurring in the jaw or joints. Note=Mutations in PTPN11 account for more than 50% of the cases. Rarely, NS is associated with juvenile myelomonocytic leukemia (JMML). NS1 inheritance is autosomal dominant.
DISEASE: Defects in PTPN11 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. It is characterized by leukocytosis with tissue infiltration and in vitro hypersensitivity of myeloid progenitors to granulocyte- macrophage colony stimulating factor.
DISEASE: Defects in PTPN11 are a cause of metachondromatosis (MC) [MIM:156250]. It is a skeletal disorder with radiologic fetarures of both multiple exostoses and Ollier disease, characterized by the presence of multiple enchondromas and osteochondroma-like lesions.
SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
SIMILARITY: Contains 2 SH2 domains.
SIMILARITY: Contains 1 tyrosine-protein phosphatase domain.
WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/PTPN11ID41910ch12q24.html";
WEB RESOURCE: Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/PTPN11";

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: PTPN11
Diseases sorted by gene-association score: noonan syndrome 1* (1613), juvenile myelomonocytic leukemia* (1600), metachondromatosis* (1378), leopard syndrome 1* (1230), noonan syndrome with multiple lentigines* (768), ptpn11-related noonan syndrome* (500), leopard syndrome* (326), noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia* (231), juvenile myelomonocytic leukemia, somatic ptpn11-related* (100), ptpn11-related leopard syndrome* (100), pulmonary valve stenosis (26), myeloid leukemia (21), myelodysplastic myeloproliferative cancer (20), leukemia (19), costello syndrome (18), neurofibromatosis-noonan syndrome (17), cardiofaciocutaneous syndrome (16), heart disease (13), villonodular synovitis (13), autosomal dominant caf au lait spots (13), bone marrow cancer (10), pulmonary valve disease (10), lymphoproliferative syndrome, x-linked, 1 (9), myelodysplastic syndrome (9), aggressive systemic mastocytosis (9), severe congenital neutropenia (8), pulmonic stenosis (7), global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies (7), childhood leukemia (7), pigmented villonodular synovitis (6), myelophthisic anemia (6), lymphoproliferative syndrome (6), myeloproliferative neoplasm (6), noma (6), dengue disease (6), pilocytic astrocytoma (6), cryptorchidism (6), neonatal leukemia (5), multiple enchondromatosis, maffucci type (5), chylothorax, congenital (5), enchondromatosis, multiple, ollier type (5), myeloproliferative syndrome, transient (5), legius syndrome (4), baraitser-winter syndrome (4), hepatocellular carcinoma (2), hematologic cancer (2), cardiomyopathy (2), cardiomyopathy, familial hypertrophic (2), tetralogy of fallot (1), leukemia, acute myeloid (1)
* = Manually curated disease association

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • D000082 Acetaminophen
  • C059514 resveratrol
  • D015655 1-Methyl-4-phenylpyridinium
  • C097240 15-deoxy-delta(12,14)-prostaglandin J2
  • C016403 2,4-dinitrotoluene
  • C023514 2,6-dinitrotoluene
  • C532162 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine
  • C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
  • C030370 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone
  • D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
          more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 52.45 RPKM in Brain - Spinal cord (cervical c-1)
Total median expression: 1254.37 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -85.70165-0.519 Picture PostScript Text
3' UTR -1149.404126-0.279 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000980 - SH2
IPR000387 - Tyr/Dual-specificity_Pase
IPR016130 - Tyr_Pase_AS
IPR012152 - Tyr_Pase_non-rcpt_typ-6/11
IPR000242 - Tyr_Pase_rcpt/non-rcpt

Pfam Domains:
PF00017 - SH2 domain
PF00102 - Protein-tyrosine phosphatase

Protein Data Bank (PDB) 3-D Structure
MuPIT help
2SHP - X-ray MuPIT 3B7O - X-ray MuPIT 3MOW - X-ray MuPIT 3O5X - X-ray 3TKZ - X-ray MuPIT 3TL0 - X-ray MuPIT


ModBase Predicted Comparative 3D Structure on Q06124
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein SequenceProtein Sequence   
AlignmentAlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0001784 phosphotyrosine binding
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005070 SH3/SH2 adaptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
GO:0031748 D1 dopamine receptor binding
GO:0043274 phospholipase binding
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0050839 cell adhesion molecule binding
GO:0051428 peptide hormone receptor binding
GO:1990782 protein tyrosine kinase binding

Biological Process:
GO:0000077 DNA damage checkpoint
GO:0000187 activation of MAPK activity
GO:0006470 protein dephosphorylation
GO:0006629 lipid metabolic process
GO:0006641 triglyceride metabolic process
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0007420 brain development
GO:0007507 heart development
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009755 hormone-mediated signaling pathway
GO:0009967 positive regulation of signal transduction
GO:0016311 dephosphorylation
GO:0019221 cytokine-mediated signaling pathway
GO:0021697 cerebellar cortex formation
GO:0030168 platelet activation
GO:0030220 platelet formation
GO:0031295 T cell costimulation
GO:0032528 microvillus organization
GO:0033277 abortive mitotic cell cycle
GO:0033628 regulation of cell adhesion mediated by integrin
GO:0033629 negative regulation of cell adhesion mediated by integrin
GO:0035264 multicellular organism growth
GO:0035265 organ growth
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035855 megakaryocyte development
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
GO:0036302 atrioventricular canal development
GO:0038127 ERBB signaling pathway
GO:0040014 regulation of multicellular organism growth
GO:0042445 hormone metabolic process
GO:0042593 glucose homeostasis
GO:0043254 regulation of protein complex assembly
GO:0045931 positive regulation of mitotic cell cycle
GO:0046676 negative regulation of insulin secretion
GO:0046825 regulation of protein export from nucleus
GO:0046854 phosphatidylinositol phosphorylation
GO:0046887 positive regulation of hormone secretion
GO:0046888 negative regulation of hormone secretion
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048013 ephrin receptor signaling pathway
GO:0048609 multicellular organismal reproductive process
GO:0048806 genitalia development
GO:0048839 inner ear development
GO:0048873 homeostasis of number of cells within a tissue
GO:0050900 leukocyte migration
GO:0051463 negative regulation of cortisol secretion
GO:0051897 positive regulation of protein kinase B signaling
GO:0060020 Bergmann glial cell differentiation
GO:0060125 negative regulation of growth hormone secretion
GO:0060325 face morphogenesis
GO:0060338 regulation of type I interferon-mediated signaling pathway
GO:0061582 intestinal epithelial cell migration
GO:0070102 interleukin-6-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071260 cellular response to mechanical stimulus
GO:0071345 cellular response to cytokine stimulus
GO:0071364 cellular response to epidermal growth factor stimulus
GO:2001275 positive regulation of glucose import in response to insulin stimulus

Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0032991 macromolecular complex


-  Descriptions from all associated GenBank mRNAs
  LP895256 - Sequence 120 from Patent EP3253886.
BC008692 - Homo sapiens protein tyrosine phosphatase, non-receptor type 11, mRNA (cDNA clone MGC:17206 IMAGE:3872007), complete cds.
L08807 - Human protein tyrosine phosphatase mRNA.
AK289854 - Homo sapiens cDNA FLJ75588 complete cds, highly similar to Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) (PTPN11), mRNA.
D13540 - Homo sapiens SH-PTP3 mRNA for protein-tyrosine phosphatase, complete cds.
L07527 - Homo sapiens protein-tyrosine phosphatase mRNA, complete cds.
X70766 - H.sapiens mRNA for phosphotyrosine phosphatase.
L03535 - Homo sapiens phosphotyrosyl-protein phosphatase (SH-PTP2) mRNA, complete cds.
AB384730 - Synthetic construct DNA, clone: pF1KB3031, Homo sapiens PTPN11 gene for protein tyrosine phosphatase, non-receptor type 11, complete cds, without stop codon, in Flexi system.
AF119855 - Homo sapiens PRO1847 mRNA, complete cds.
BT007106 - Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) mRNA, complete cds.
JD388665 - Sequence 369689 from Patent EP1572962.
JD142398 - Sequence 123422 from Patent EP1572962.
JD495445 - Sequence 476469 from Patent EP1572962.
EU779707 - Homo sapiens protein tyrosine phosphatase-2 (PTPN11) mRNA, partial cds.
EU779708 - Homo sapiens protein tyrosine phosphatase-2 (PTPN11) mRNA, complete cds.
EU779706 - Homo sapiens protein tyrosine phosphatase-2 (PTPN11) mRNA, partial cds.
JD331337 - Sequence 312361 from Patent EP1572962.
JD181404 - Sequence 162428 from Patent EP1572962.
JD348280 - Sequence 329304 from Patent EP1572962.
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LY595192 - KR 1020180133840-A/4616: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
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LY595194 - KR 1020180133840-A/4618: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595195 - KR 1020180133840-A/4619: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595196 - KR 1020180133840-A/4620: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595197 - KR 1020180133840-A/4621: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595198 - KR 1020180133840-A/4622: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595199 - KR 1020180133840-A/4623: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595200 - KR 1020180133840-A/4624: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595201 - KR 1020180133840-A/4625: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595202 - KR 1020180133840-A/4626: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595203 - KR 1020180133840-A/4627: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595204 - KR 1020180133840-A/4628: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595205 - KR 1020180133840-A/4629: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595206 - KR 1020180133840-A/4630: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595207 - KR 1020180133840-A/4631: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595208 - KR 1020180133840-A/4632: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595209 - KR 1020180133840-A/4633: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595254 - KR 1020180133840-A/4678: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595255 - KR 1020180133840-A/4679: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595256 - KR 1020180133840-A/4680: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595257 - KR 1020180133840-A/4681: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595258 - KR 1020180133840-A/4682: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595259 - KR 1020180133840-A/4683: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595260 - KR 1020180133840-A/4684: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595261 - KR 1020180133840-A/4685: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595262 - KR 1020180133840-A/4686: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595263 - KR 1020180133840-A/4687: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595273 - KR 1020180133840-A/4697: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595274 - KR 1020180133840-A/4698: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595275 - KR 1020180133840-A/4699: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595276 - KR 1020180133840-A/4700: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595277 - KR 1020180133840-A/4701: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595278 - KR 1020180133840-A/4702: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595279 - KR 1020180133840-A/4703: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595280 - KR 1020180133840-A/4704: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595281 - KR 1020180133840-A/4705: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595282 - KR 1020180133840-A/4706: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595283 - KR 1020180133840-A/4707: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595284 - KR 1020180133840-A/4708: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595298 - KR 1020180133840-A/4722: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595299 - KR 1020180133840-A/4723: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595300 - KR 1020180133840-A/4724: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595301 - KR 1020180133840-A/4725: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595302 - KR 1020180133840-A/4726: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595303 - KR 1020180133840-A/4727: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595304 - KR 1020180133840-A/4728: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595305 - KR 1020180133840-A/4729: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595306 - KR 1020180133840-A/4730: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595307 - KR 1020180133840-A/4731: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595308 - KR 1020180133840-A/4732: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595317 - KR 1020180133840-A/4741: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595318 - KR 1020180133840-A/4742: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595319 - KR 1020180133840-A/4743: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595320 - KR 1020180133840-A/4744: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595321 - KR 1020180133840-A/4745: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595322 - KR 1020180133840-A/4746: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595323 - KR 1020180133840-A/4747: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595324 - KR 1020180133840-A/4748: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595325 - KR 1020180133840-A/4749: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595326 - KR 1020180133840-A/4750: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595327 - KR 1020180133840-A/4751: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595329 - KR 1020180133840-A/4753: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595330 - KR 1020180133840-A/4754: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595331 - KR 1020180133840-A/4755: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595332 - KR 1020180133840-A/4756: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
S78088 - Homo sapiens protein-tyrosine phosphatase (BPTP-3) mRNA, partial cds.
S39383 - protein tyrosine phosphatase {clone CL-2B} [human, colon, mRNA Partial, 90 nt].
JD141375 - Sequence 122399 from Patent EP1572962.
JD268791 - Sequence 249815 from Patent EP1572962.
JD301957 - Sequence 282981 from Patent EP1572962.
JD037566 - Sequence 18590 from Patent EP1572962.
JD560375 - Sequence 541399 from Patent EP1572962.
JD562776 - Sequence 543800 from Patent EP1572962.
JD240151 - Sequence 221175 from Patent EP1572962.
BX537632 - Homo sapiens mRNA; cDNA DKFZp686G13208 (from clone DKFZp686G13208).
BC025181 - Homo sapiens protein tyrosine phosphatase, non-receptor type 11, mRNA (cDNA clone IMAGE:5114644), complete cds.
BC030949 - Homo sapiens protein tyrosine phosphatase, non-receptor type 11, mRNA (cDNA clone IMAGE:4658625), complete cds.
BC007869 - Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), mRNA (cDNA clone IMAGE:4303171).
AK312147 - Homo sapiens cDNA, FLJ92431.
JD139087 - Sequence 120111 from Patent EP1572962.
KJ901681 - Synthetic construct Homo sapiens clone ccsbBroadEn_11075 PTPN11 gene, encodes complete protein.
JD088448 - Sequence 69472 from Patent EP1572962.
JD344857 - Sequence 325881 from Patent EP1572962.
U79291 - Human clone 23721 mRNA sequence.
JD019366 - Sequence 390 from Patent EP1572962.
JD386658 - Sequence 367682 from Patent EP1572962.
JD154649 - Sequence 135673 from Patent EP1572962.
JD034169 - Sequence 15193 from Patent EP1572962.
JD037556 - Sequence 18580 from Patent EP1572962.
JD299058 - Sequence 280082 from Patent EP1572962.
JD519634 - Sequence 500658 from Patent EP1572962.
JD537518 - Sequence 518542 from Patent EP1572962.
JD314004 - Sequence 295028 from Patent EP1572962.
MA872925 - JP 2018536436-A/4761: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872926 - JP 2018536436-A/4762: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872927 - JP 2018536436-A/4763: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872928 - JP 2018536436-A/4764: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872936 - JP 2018536436-A/4772: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872937 - JP 2018536436-A/4773: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872944 - JP 2018536436-A/4780: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872945 - JP 2018536436-A/4781: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872946 - JP 2018536436-A/4782: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872947 - JP 2018536436-A/4783: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872948 - JP 2018536436-A/4784: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872949 - JP 2018536436-A/4785: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872950 - JP 2018536436-A/4786: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872951 - JP 2018536436-A/4787: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872962 - JP 2018536436-A/4798: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872963 - JP 2018536436-A/4799: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872964 - JP 2018536436-A/4800: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872965 - JP 2018536436-A/4801: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872966 - JP 2018536436-A/4802: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872972 - JP 2018536436-A/4808: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872973 - JP 2018536436-A/4809: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872974 - JP 2018536436-A/4810: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872975 - JP 2018536436-A/4811: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872976 - JP 2018536436-A/4812: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872977 - JP 2018536436-A/4813: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872978 - JP 2018536436-A/4814: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872979 - JP 2018536436-A/4815: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872980 - JP 2018536436-A/4816: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872981 - JP 2018536436-A/4817: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872982 - JP 2018536436-A/4818: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872983 - JP 2018536436-A/4819: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872984 - JP 2018536436-A/4820: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872985 - JP 2018536436-A/4821: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872986 - JP 2018536436-A/4822: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872987 - JP 2018536436-A/4823: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872988 - JP 2018536436-A/4824: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872989 - JP 2018536436-A/4825: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872990 - JP 2018536436-A/4826: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872991 - JP 2018536436-A/4827: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA872992 - JP 2018536436-A/4828: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873045 - JP 2018536436-A/4881: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873046 - JP 2018536436-A/4882: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873047 - JP 2018536436-A/4883: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873048 - JP 2018536436-A/4884: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873049 - JP 2018536436-A/4885: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873050 - JP 2018536436-A/4886: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873051 - JP 2018536436-A/4887: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873058 - JP 2018536436-A/4894: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873059 - JP 2018536436-A/4895: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873060 - JP 2018536436-A/4896: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873061 - JP 2018536436-A/4897: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873062 - JP 2018536436-A/4898: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873063 - JP 2018536436-A/4899: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873064 - JP 2018536436-A/4900: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873065 - JP 2018536436-A/4901: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873066 - JP 2018536436-A/4902: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873067 - JP 2018536436-A/4903: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873068 - JP 2018536436-A/4904: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873069 - JP 2018536436-A/4905: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873080 - JP 2018536436-A/4916: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873081 - JP 2018536436-A/4917: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873082 - JP 2018536436-A/4918: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873083 - JP 2018536436-A/4919: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873096 - JP 2018536436-A/4932: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873097 - JP 2018536436-A/4933: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873098 - JP 2018536436-A/4934: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873104 - JP 2018536436-A/4940: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873105 - JP 2018536436-A/4941: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873106 - JP 2018536436-A/4942: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873107 - JP 2018536436-A/4943: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873108 - JP 2018536436-A/4944: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873109 - JP 2018536436-A/4945: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873110 - JP 2018536436-A/4946: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873111 - JP 2018536436-A/4947: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873112 - JP 2018536436-A/4948: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873116 - JP 2018536436-A/4952: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873117 - JP 2018536436-A/4953: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873118 - JP 2018536436-A/4954: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873119 - JP 2018536436-A/4955: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873120 - JP 2018536436-A/4956: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873121 - JP 2018536436-A/4957: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873122 - JP 2018536436-A/4958: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873123 - JP 2018536436-A/4959: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873124 - JP 2018536436-A/4960: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873125 - JP 2018536436-A/4961: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873126 - JP 2018536436-A/4962: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873127 - JP 2018536436-A/4963: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873128 - JP 2018536436-A/4964: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873129 - JP 2018536436-A/4965: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873131 - JP 2018536436-A/4967: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873132 - JP 2018536436-A/4968: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873133 - JP 2018536436-A/4969: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873134 - JP 2018536436-A/4970: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873135 - JP 2018536436-A/4971: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873136 - JP 2018536436-A/4972: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873137 - JP 2018536436-A/4973: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873138 - JP 2018536436-A/4974: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873139 - JP 2018536436-A/4975: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873140 - JP 2018536436-A/4976: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873141 - JP 2018536436-A/4977: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873142 - JP 2018536436-A/4978: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873143 - JP 2018536436-A/4979: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873144 - JP 2018536436-A/4980: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873145 - JP 2018536436-A/4981: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873146 - JP 2018536436-A/4982: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873147 - JP 2018536436-A/4983: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873148 - JP 2018536436-A/4984: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873149 - JP 2018536436-A/4985: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873150 - JP 2018536436-A/4986: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873151 - JP 2018536436-A/4987: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873152 - JP 2018536436-A/4988: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873153 - JP 2018536436-A/4989: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873154 - JP 2018536436-A/4990: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873155 - JP 2018536436-A/4991: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873156 - JP 2018536436-A/4992: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873157 - JP 2018536436-A/4993: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873158 - JP 2018536436-A/4994: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873159 - JP 2018536436-A/4995: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873160 - JP 2018536436-A/4996: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873161 - JP 2018536436-A/4997: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873162 - JP 2018536436-A/4998: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873163 - JP 2018536436-A/4999: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873164 - JP 2018536436-A/5000: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873165 - JP 2018536436-A/5001: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873166 - JP 2018536436-A/5002: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873167 - JP 2018536436-A/5003: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873168 - JP 2018536436-A/5004: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873169 - JP 2018536436-A/5005: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873170 - JP 2018536436-A/5006: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873171 - JP 2018536436-A/5007: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873172 - JP 2018536436-A/5008: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873173 - JP 2018536436-A/5009: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873174 - JP 2018536436-A/5010: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873175 - JP 2018536436-A/5011: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873176 - JP 2018536436-A/5012: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873177 - JP 2018536436-A/5013: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873178 - JP 2018536436-A/5014: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873179 - JP 2018536436-A/5015: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873180 - JP 2018536436-A/5016: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873181 - JP 2018536436-A/5017: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873182 - JP 2018536436-A/5018: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873183 - JP 2018536436-A/5019: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873184 - JP 2018536436-A/5020: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873185 - JP 2018536436-A/5021: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873186 - JP 2018536436-A/5022: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873187 - JP 2018536436-A/5023: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873188 - JP 2018536436-A/5024: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873189 - JP 2018536436-A/5025: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873190 - JP 2018536436-A/5026: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873191 - JP 2018536436-A/5027: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873192 - JP 2018536436-A/5028: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873193 - JP 2018536436-A/5029: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873194 - JP 2018536436-A/5030: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873195 - JP 2018536436-A/5031: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873196 - JP 2018536436-A/5032: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873197 - JP 2018536436-A/5033: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873198 - JP 2018536436-A/5034: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873199 - JP 2018536436-A/5035: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873200 - JP 2018536436-A/5036: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873201 - JP 2018536436-A/5037: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873202 - JP 2018536436-A/5038: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873203 - JP 2018536436-A/5039: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873204 - JP 2018536436-A/5040: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873205 - JP 2018536436-A/5041: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873206 - JP 2018536436-A/5042: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873207 - JP 2018536436-A/5043: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873208 - JP 2018536436-A/5044: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873209 - JP 2018536436-A/5045: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873210 - JP 2018536436-A/5046: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873211 - JP 2018536436-A/5047: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873212 - JP 2018536436-A/5048: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873213 - JP 2018536436-A/5049: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873216 - JP 2018536436-A/5052: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873217 - JP 2018536436-A/5053: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873218 - JP 2018536436-A/5054: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873219 - JP 2018536436-A/5055: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873220 - JP 2018536436-A/5056: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873221 - JP 2018536436-A/5057: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873222 - JP 2018536436-A/5058: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873223 - JP 2018536436-A/5059: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873224 - JP 2018536436-A/5060: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873225 - JP 2018536436-A/5061: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873226 - JP 2018536436-A/5062: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873227 - JP 2018536436-A/5063: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873228 - JP 2018536436-A/5064: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873229 - JP 2018536436-A/5065: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873230 - JP 2018536436-A/5066: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873231 - JP 2018536436-A/5067: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873232 - JP 2018536436-A/5068: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873233 - JP 2018536436-A/5069: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873234 - JP 2018536436-A/5070: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873235 - JP 2018536436-A/5071: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873236 - JP 2018536436-A/5072: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873237 - JP 2018536436-A/5073: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873238 - JP 2018536436-A/5074: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873240 - JP 2018536436-A/5076: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873241 - JP 2018536436-A/5077: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873242 - JP 2018536436-A/5078: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873243 - JP 2018536436-A/5079: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873244 - JP 2018536436-A/5080: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873245 - JP 2018536436-A/5081: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873246 - JP 2018536436-A/5082: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873247 - JP 2018536436-A/5083: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873248 - JP 2018536436-A/5084: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873249 - JP 2018536436-A/5085: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873250 - JP 2018536436-A/5086: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873251 - JP 2018536436-A/5087: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873252 - JP 2018536436-A/5088: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873253 - JP 2018536436-A/5089: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873254 - JP 2018536436-A/5090: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873255 - JP 2018536436-A/5091: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873256 - JP 2018536436-A/5092: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873257 - JP 2018536436-A/5093: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873258 - JP 2018536436-A/5094: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873259 - JP 2018536436-A/5095: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873260 - JP 2018536436-A/5096: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873261 - JP 2018536436-A/5097: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873266 - JP 2018536436-A/5102: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873267 - JP 2018536436-A/5103: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873268 - JP 2018536436-A/5104: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873269 - JP 2018536436-A/5105: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873270 - JP 2018536436-A/5106: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873271 - JP 2018536436-A/5107: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873272 - JP 2018536436-A/5108: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873273 - JP 2018536436-A/5109: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873274 - JP 2018536436-A/5110: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873275 - JP 2018536436-A/5111: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873276 - JP 2018536436-A/5112: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873277 - JP 2018536436-A/5113: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873278 - JP 2018536436-A/5114: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873279 - JP 2018536436-A/5115: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873280 - JP 2018536436-A/5116: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873281 - JP 2018536436-A/5117: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873282 - JP 2018536436-A/5118: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873283 - JP 2018536436-A/5119: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873284 - JP 2018536436-A/5120: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873285 - JP 2018536436-A/5121: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873286 - JP 2018536436-A/5122: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873287 - JP 2018536436-A/5123: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873288 - JP 2018536436-A/5124: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873289 - JP 2018536436-A/5125: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873290 - JP 2018536436-A/5126: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
MA873291 - JP 2018536436-A/5127: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595337 - KR 1020180133840-A/4761: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595338 - KR 1020180133840-A/4762: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595339 - KR 1020180133840-A/4763: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595340 - KR 1020180133840-A/4764: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595348 - KR 1020180133840-A/4772: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595349 - KR 1020180133840-A/4773: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595356 - KR 1020180133840-A/4780: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595357 - KR 1020180133840-A/4781: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595358 - KR 1020180133840-A/4782: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595359 - KR 1020180133840-A/4783: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595360 - KR 1020180133840-A/4784: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595361 - KR 1020180133840-A/4785: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595362 - KR 1020180133840-A/4786: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595363 - KR 1020180133840-A/4787: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595374 - KR 1020180133840-A/4798: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595375 - KR 1020180133840-A/4799: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595376 - KR 1020180133840-A/4800: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595377 - KR 1020180133840-A/4801: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595378 - KR 1020180133840-A/4802: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595384 - KR 1020180133840-A/4808: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595385 - KR 1020180133840-A/4809: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595386 - KR 1020180133840-A/4810: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595387 - KR 1020180133840-A/4811: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595388 - KR 1020180133840-A/4812: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595389 - KR 1020180133840-A/4813: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595390 - KR 1020180133840-A/4814: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595391 - KR 1020180133840-A/4815: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595392 - KR 1020180133840-A/4816: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595393 - KR 1020180133840-A/4817: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595394 - KR 1020180133840-A/4818: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595395 - KR 1020180133840-A/4819: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595396 - KR 1020180133840-A/4820: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595397 - KR 1020180133840-A/4821: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595398 - KR 1020180133840-A/4822: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595399 - KR 1020180133840-A/4823: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595400 - KR 1020180133840-A/4824: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595401 - KR 1020180133840-A/4825: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595402 - KR 1020180133840-A/4826: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595403 - KR 1020180133840-A/4827: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595404 - KR 1020180133840-A/4828: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595457 - KR 1020180133840-A/4881: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595458 - KR 1020180133840-A/4882: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595459 - KR 1020180133840-A/4883: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595460 - KR 1020180133840-A/4884: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595461 - KR 1020180133840-A/4885: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595462 - KR 1020180133840-A/4886: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595463 - KR 1020180133840-A/4887: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595470 - KR 1020180133840-A/4894: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595471 - KR 1020180133840-A/4895: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595472 - KR 1020180133840-A/4896: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595473 - KR 1020180133840-A/4897: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595474 - KR 1020180133840-A/4898: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595475 - KR 1020180133840-A/4899: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595476 - KR 1020180133840-A/4900: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595477 - KR 1020180133840-A/4901: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595478 - KR 1020180133840-A/4902: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595479 - KR 1020180133840-A/4903: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595480 - KR 1020180133840-A/4904: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595481 - KR 1020180133840-A/4905: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595492 - KR 1020180133840-A/4916: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595493 - KR 1020180133840-A/4917: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595494 - KR 1020180133840-A/4918: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595495 - KR 1020180133840-A/4919: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595508 - KR 1020180133840-A/4932: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595509 - KR 1020180133840-A/4933: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595510 - KR 1020180133840-A/4934: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595516 - KR 1020180133840-A/4940: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595517 - KR 1020180133840-A/4941: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595518 - KR 1020180133840-A/4942: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595519 - KR 1020180133840-A/4943: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595520 - KR 1020180133840-A/4944: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595521 - KR 1020180133840-A/4945: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595522 - KR 1020180133840-A/4946: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595523 - KR 1020180133840-A/4947: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595524 - KR 1020180133840-A/4948: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595528 - KR 1020180133840-A/4952: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595529 - KR 1020180133840-A/4953: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595530 - KR 1020180133840-A/4954: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595531 - KR 1020180133840-A/4955: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595532 - KR 1020180133840-A/4956: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595533 - KR 1020180133840-A/4957: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595534 - KR 1020180133840-A/4958: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595535 - KR 1020180133840-A/4959: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595536 - KR 1020180133840-A/4960: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595537 - KR 1020180133840-A/4961: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595538 - KR 1020180133840-A/4962: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595539 - KR 1020180133840-A/4963: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595540 - KR 1020180133840-A/4964: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595541 - KR 1020180133840-A/4965: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595543 - KR 1020180133840-A/4967: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595544 - KR 1020180133840-A/4968: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595545 - KR 1020180133840-A/4969: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595546 - KR 1020180133840-A/4970: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595547 - KR 1020180133840-A/4971: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595548 - KR 1020180133840-A/4972: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595549 - KR 1020180133840-A/4973: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595550 - KR 1020180133840-A/4974: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595551 - KR 1020180133840-A/4975: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595552 - KR 1020180133840-A/4976: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595553 - KR 1020180133840-A/4977: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595554 - KR 1020180133840-A/4978: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595555 - KR 1020180133840-A/4979: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595556 - KR 1020180133840-A/4980: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595557 - KR 1020180133840-A/4981: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595558 - KR 1020180133840-A/4982: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595559 - KR 1020180133840-A/4983: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595560 - KR 1020180133840-A/4984: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595561 - KR 1020180133840-A/4985: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595562 - KR 1020180133840-A/4986: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595563 - KR 1020180133840-A/4987: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595564 - KR 1020180133840-A/4988: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595565 - KR 1020180133840-A/4989: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595566 - KR 1020180133840-A/4990: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595567 - KR 1020180133840-A/4991: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595568 - KR 1020180133840-A/4992: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595569 - KR 1020180133840-A/4993: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595570 - KR 1020180133840-A/4994: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595571 - KR 1020180133840-A/4995: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595572 - KR 1020180133840-A/4996: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595573 - KR 1020180133840-A/4997: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595574 - KR 1020180133840-A/4998: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595575 - KR 1020180133840-A/4999: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595576 - KR 1020180133840-A/5000: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595577 - KR 1020180133840-A/5001: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595578 - KR 1020180133840-A/5002: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595579 - KR 1020180133840-A/5003: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595580 - KR 1020180133840-A/5004: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595581 - KR 1020180133840-A/5005: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595582 - KR 1020180133840-A/5006: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595583 - KR 1020180133840-A/5007: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595584 - KR 1020180133840-A/5008: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595585 - KR 1020180133840-A/5009: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595586 - KR 1020180133840-A/5010: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595587 - KR 1020180133840-A/5011: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595588 - KR 1020180133840-A/5012: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595589 - KR 1020180133840-A/5013: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595590 - KR 1020180133840-A/5014: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595591 - KR 1020180133840-A/5015: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595592 - KR 1020180133840-A/5016: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595593 - KR 1020180133840-A/5017: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595594 - KR 1020180133840-A/5018: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595595 - KR 1020180133840-A/5019: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595596 - KR 1020180133840-A/5020: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595597 - KR 1020180133840-A/5021: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595598 - KR 1020180133840-A/5022: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595599 - KR 1020180133840-A/5023: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595600 - KR 1020180133840-A/5024: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595601 - KR 1020180133840-A/5025: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595602 - KR 1020180133840-A/5026: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595603 - KR 1020180133840-A/5027: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595604 - KR 1020180133840-A/5028: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595605 - KR 1020180133840-A/5029: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595606 - KR 1020180133840-A/5030: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595607 - KR 1020180133840-A/5031: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595608 - KR 1020180133840-A/5032: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595609 - KR 1020180133840-A/5033: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595610 - KR 1020180133840-A/5034: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595611 - KR 1020180133840-A/5035: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595612 - KR 1020180133840-A/5036: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595613 - KR 1020180133840-A/5037: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595614 - KR 1020180133840-A/5038: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595615 - KR 1020180133840-A/5039: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595616 - KR 1020180133840-A/5040: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595617 - KR 1020180133840-A/5041: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595618 - KR 1020180133840-A/5042: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595619 - KR 1020180133840-A/5043: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595620 - KR 1020180133840-A/5044: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595621 - KR 1020180133840-A/5045: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595622 - KR 1020180133840-A/5046: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595623 - KR 1020180133840-A/5047: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595624 - KR 1020180133840-A/5048: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595625 - KR 1020180133840-A/5049: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595628 - KR 1020180133840-A/5052: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595629 - KR 1020180133840-A/5053: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595630 - KR 1020180133840-A/5054: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595631 - KR 1020180133840-A/5055: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595632 - KR 1020180133840-A/5056: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595633 - KR 1020180133840-A/5057: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595634 - KR 1020180133840-A/5058: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595635 - KR 1020180133840-A/5059: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595636 - KR 1020180133840-A/5060: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595637 - KR 1020180133840-A/5061: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595638 - KR 1020180133840-A/5062: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595639 - KR 1020180133840-A/5063: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595640 - KR 1020180133840-A/5064: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595641 - KR 1020180133840-A/5065: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595642 - KR 1020180133840-A/5066: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595643 - KR 1020180133840-A/5067: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595644 - KR 1020180133840-A/5068: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595645 - KR 1020180133840-A/5069: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595646 - KR 1020180133840-A/5070: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595647 - KR 1020180133840-A/5071: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595648 - KR 1020180133840-A/5072: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595649 - KR 1020180133840-A/5073: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595650 - KR 1020180133840-A/5074: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595652 - KR 1020180133840-A/5076: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595653 - KR 1020180133840-A/5077: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595654 - KR 1020180133840-A/5078: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595655 - KR 1020180133840-A/5079: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595656 - KR 1020180133840-A/5080: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595657 - KR 1020180133840-A/5081: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595658 - KR 1020180133840-A/5082: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595659 - KR 1020180133840-A/5083: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595660 - KR 1020180133840-A/5084: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595661 - KR 1020180133840-A/5085: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595662 - KR 1020180133840-A/5086: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595663 - KR 1020180133840-A/5087: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595664 - KR 1020180133840-A/5088: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595665 - KR 1020180133840-A/5089: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595666 - KR 1020180133840-A/5090: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595667 - KR 1020180133840-A/5091: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595668 - KR 1020180133840-A/5092: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595669 - KR 1020180133840-A/5093: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595670 - KR 1020180133840-A/5094: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595671 - KR 1020180133840-A/5095: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595672 - KR 1020180133840-A/5096: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595673 - KR 1020180133840-A/5097: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595678 - KR 1020180133840-A/5102: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595679 - KR 1020180133840-A/5103: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595680 - KR 1020180133840-A/5104: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595681 - KR 1020180133840-A/5105: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595682 - KR 1020180133840-A/5106: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595683 - KR 1020180133840-A/5107: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595684 - KR 1020180133840-A/5108: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595685 - KR 1020180133840-A/5109: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595686 - KR 1020180133840-A/5110: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595687 - KR 1020180133840-A/5111: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595688 - KR 1020180133840-A/5112: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595689 - KR 1020180133840-A/5113: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595690 - KR 1020180133840-A/5114: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595691 - KR 1020180133840-A/5115: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595692 - KR 1020180133840-A/5116: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595693 - KR 1020180133840-A/5117: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595694 - KR 1020180133840-A/5118: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595695 - KR 1020180133840-A/5119: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595696 - KR 1020180133840-A/5120: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595697 - KR 1020180133840-A/5121: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595698 - KR 1020180133840-A/5122: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595699 - KR 1020180133840-A/5123: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595700 - KR 1020180133840-A/5124: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595701 - KR 1020180133840-A/5125: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595702 - KR 1020180133840-A/5126: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.
LY595703 - KR 1020180133840-A/5127: COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa04630 - Jak-STAT signaling pathway
hsa04650 - Natural killer cell mediated cytotoxicity
hsa04670 - Leukocyte transendothelial migration
hsa04722 - Neurotrophin signaling pathway
hsa04920 - Adipocytokine signaling pathway
hsa05120 - Epithelial cell signaling in Helicobacter pylori infection
hsa05211 - Renal cell carcinoma
hsa05220 - Chronic myeloid leukemia

BioCarta from NCI Cancer Genome Anatomy Project
h_metPathway - Signaling of Hepatocyte Growth Factor Receptor
h_insulinPathway - Insulin Signaling Pathway
h_ctla4Pathway - The Co-Stimulatory Signal During T-cell Activation
h_igf1Pathway - IGF-1 Signaling Pathway
h_il6Pathway - IL 6 signaling pathway

Reactome (by CSHL, EBI, and GO)

Protein Q06124 (Reactome details) participates in the following event(s):

R-HSA-177944 Activation of SHP2 through the binding to phospho-Gab1
R-HSA-186778 SHP2 binds to the active receptor
R-HSA-204873 Interaction of Tie2 and Shp2
R-HSA-205238 SHP2 interacts with p-KIT
R-HSA-210294 Interaction of PECAM-1 and SHP-2
R-HSA-388829 SHP2 phosphatase binds CTLA-4
R-HSA-418863 Shp2 binds pUnc5C
R-HSA-914022 SHP2 can recruit GRB2
R-HSA-1112708 PTPN11 binds p-Y759-IL6ST
R-HSA-1369114 PRLR binds SHP2 (PTPN11)
R-HSA-2671747 Phosphorylated LEPR Binds SHP2 (PTPN11)
R-HSA-5654584 Activated FGFR1:p-FRS bind to PPTN11
R-HSA-5654608 Activated FGFR2:p-FRS bind to PPTN11
R-HSA-5654633 Activated FGFR3:p-FRS bind to PPTN11
R-HSA-5654658 Activated FGFR4:p-FRS bind to PPTN11
R-HSA-8855508 p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11
R-HSA-8865994 GAB1 binds PTPN11
R-HSA-8987132 IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11
R-HSA-9031981 NTRK2-phosphorylated FRS2 binds PTPN11
R-HSA-8937744 PTPN11 binds p-7Y-RUNX1
R-HSA-8937767 PTPN11 dephosphorylates RUNX1
R-HSA-177924 Dephosphorylation of Gab1 by SHP2
R-HSA-177935 SHP2 dephosphorylates Tyr 992 on EGFR
R-HSA-1433488 Phosphorylation of SHP2 by SFKs
R-HSA-1112690 PTPN11 binds CBL
R-HSA-1112703 PTPN11 is phosphorylated
R-HSA-1369115 SHP2 is phosphorylated
R-HSA-2671742 JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin
R-HSA-5654587 Activated FGFR1:p-FRS phosphorylates PPTN11
R-HSA-5654607 Activated FGFR2 phosphorylates PPTN11
R-HSA-5654631 Activated FGFR3 phosphorylates PPTN11
R-HSA-5654655 Activated FGFR4 phosphorylates PPTN11
R-HSA-389759 Interaction of SHP-1 or SHP-2 with phospho PD-1
R-HSA-389941 SHP-1 and SHP-2 bind pBTLA
R-HSA-391150 p-4Y-SIRPA:CD47 binds PTPN6,PTPN11
R-HSA-909738 SHP1 and SHP2 bind the common beta chain
R-HSA-5684169 G6B binds PTPN6,PTPN11
R-HSA-997309 Dephosphorylation of STAT1 by SHP2
R-HSA-1549564 PPTN11 dephosphorylates SPRY2
R-HSA-1433428 GRB2 is indirectly recruited to p-KIT through SHP2
R-HSA-5654620 Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1
R-HSA-5654729 p-CBL:GRB2 binds p-FRS2:activated FGFR2
R-HSA-5654641 Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1
R-HSA-5654730 p-CBL:GRB2 binds p-FRS2:activated FGFR3
R-HSA-5654594 Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1
R-HSA-5654673 p-CBL:GRB2 binds p-FRS2:activated FGFR1
R-HSA-5654667 Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1
R-HSA-5654734 p-CBL:GRB2 binds p-FRS2:activated FGFR4
R-HSA-177923 Sustained activation of SRC kinase by SHP2
R-HSA-177926 Dephosphorylation of PAG by SHP2
R-HSA-914036 SHP1 and SHP2 dephosphorylate Y628 of IL3RB
R-HSA-877308 Dephosphorylation of JAKs by PTPs
R-HSA-205234 Indirect recruitment of GAB2 to p-KIT
R-HSA-5654622 Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA
R-HSA-5654677 CBL ubiquitinates FRS2 and FGFR2
R-HSA-5654643 Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA
R-HSA-5654679 CBL ubiquitinates FRS2 and FGFR3
R-HSA-5654596 Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA
R-HSA-5654672 CBL ubiquitinates FRS2 and FGFR1
R-HSA-5654669 Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA
R-HSA-5654684 CBL ubiquitinates FRS2 and FGFR4
R-HSA-389758 Dephosphorylation of CD3-zeta by PD-1 bound phosphatases
R-HSA-1562641 Indirect recruitment of PI3K to KIT via p(Y)-GAB2
R-HSA-5654697 FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3
R-HSA-5654709 FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3
R-HSA-5654692 FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3
R-HSA-5654714 FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3
R-HSA-109699 PI3K-containing complexes phosphorylate PIP2 to PIP3
R-HSA-1433514 Synthesis of PIP3 from PIP2 by PI3K
R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity
R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3
R-HSA-180292 GAB1 signalosome
R-HSA-186763 Downstream signal transduction
R-HSA-210993 Tie2 Signaling
R-HSA-1433557 Signaling by SCF-KIT
R-HSA-210990 PECAM1 interactions
R-HSA-432142 Platelet sensitization by LDL
R-HSA-389513 CTLA4 inhibitory signaling
R-HSA-418886 Netrin mediated repulsion signals
R-HSA-512988 Interleukin-3, 5 and GM-CSF signaling
R-HSA-1059683 Interleukin-6 signaling
R-HSA-1170546 Prolactin receptor signaling
R-HSA-2586552 Signaling by Leptin
R-HSA-5654693 FRS-mediated FGFR1 signaling
R-HSA-5654700 FRS-mediated FGFR2 signaling
R-HSA-5654706 FRS-mediated FGFR3 signaling
R-HSA-5654712 FRS-mediated FGFR4 signaling
R-HSA-8853659 RET signaling
R-HSA-8865999 MET activates PTPN11
R-HSA-8854691 Interleukin-20 family signaling
R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3
R-HSA-8934593 Regulation of RUNX1 Expression and Activity
R-HSA-389948 PD-1 signaling
R-HSA-388841 Costimulation by the CD28 family
R-HSA-391160 Signal regulatory protein family interactions
R-HSA-114604 GPVI-mediated activation cascade
R-HSA-177929 Signaling by EGFR
R-HSA-186797 Signaling by PDGF
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-418346 Platelet homeostasis
R-HSA-373752 Netrin-1 signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-6783589 Interleukin-6 family signaling
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-5654687 Downstream signaling of activated FGFR1
R-HSA-5654696 Downstream signaling of activated FGFR2
R-HSA-5654708 Downstream signaling of activated FGFR3
R-HSA-5654716 Downstream signaling of activated FGFR4
R-HSA-422475 Axon guidance
R-HSA-6806834 Signaling by MET
R-HSA-9006115 Signaling by NTRK2 (TRKB)
R-HSA-912694 Regulation of IFNA signaling
R-HSA-1295596 Spry regulation of FGF signaling
R-HSA-5654695 PI-3K cascade:FGFR2
R-HSA-5654727 Negative regulation of FGFR2 signaling
R-HSA-5654710 PI-3K cascade:FGFR3
R-HSA-5654732 Negative regulation of FGFR3 signaling
R-HSA-5654689 PI-3K cascade:FGFR1
R-HSA-5654726 Negative regulation of FGFR1 signaling
R-HSA-5654720 PI-3K cascade:FGFR4
R-HSA-5654733 Negative regulation of FGFR4 signaling
R-HSA-9008059 Interleukin-37 signaling
R-HSA-8878171 Transcriptional regulation by RUNX1
R-HSA-1280218 Adaptive Immune System
R-HSA-1500931 Cell-Cell communication
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-877312 Regulation of IFNG signaling
R-HSA-109582 Hemostasis
R-HSA-168256 Immune System
R-HSA-5654736 Signaling by FGFR1
R-HSA-5654738 Signaling by FGFR2
R-HSA-5654741 Signaling by FGFR3
R-HSA-5654743 Signaling by FGFR4
R-HSA-1266738 Developmental Biology
R-HSA-166520 Signaling by NTRKs
R-HSA-909733 Interferon alpha/beta signaling
R-HSA-446652 Interleukin-1 family signaling
R-HSA-212436 Generic Transcription Pathway
R-HSA-877300 Interferon gamma signaling
R-HSA-190236 Signaling by FGFR
R-HSA-913531 Interferon Signaling
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-109704 PI3K Cascade
R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-HSA-112399 IRS-mediated signalling
R-HSA-2219528 PI3K/AKT Signaling in Cancer
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-199418 Negative regulation of the PI3K/AKT network
R-HSA-74751 Insulin receptor signalling cascade
R-HSA-2428928 IRS-related events triggered by IGF1R
R-HSA-5663202 Diseases of signal transduction
R-HSA-74752 Signaling by Insulin receptor
R-HSA-2428924 IGF1R signaling cascade
R-HSA-1643685 Disease
R-HSA-2404192 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)

-  Other Names for This Gene
  Alternate Gene Symbols: A8K1D9, ENST00000351677.1, ENST00000351677.2, ENST00000351677.3, ENST00000351677.4, ENST00000351677.5, ENST00000351677.6, NM_002834, PTN11_HUMAN, PTP2C, Q06124, Q96HD7, SHPTP2, uc001ttx.1, uc001ttx.2, uc001ttx.3, uc001ttx.4, uc001ttx.5
UCSC ID: ENST00000351677.7
RefSeq Accession: NM_002834
Protein: Q06124 (aka PTN11_HUMAN or PTNB_HUMAN)
CCDS: CCDS9163.1, CCDS81741.1

-  GeneReviews for This Gene
  GeneReviews article(s) related to gene PTPN11:
leopard (Noonan Syndrome with Multiple Lentigines)
noonan (Noonan Syndrome)

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.