Human Gene C14orf28 (ENST00000325192.8) from GENCODE V44
  Description: Homo sapiens chromosome 14 open reading frame 28 (C14orf28), mRNA. (from RefSeq NM_001017923)
Gencode Transcript: ENST00000325192.8
Gencode Gene: ENSG00000179476.8
Transcript (Including UTRs)
   Position: hg38 chr14:44,897,275-44,907,257 Size: 9,983 Total Exon Count: 5 Strand: +
Coding Region
   Position: hg38 chr14:44,900,436-44,905,550 Size: 5,115 Coding Exon Count: 4 

Page IndexSequence and LinksPrimersCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:44,897,275-44,907,257)mRNA (may differ from genome)Protein (310 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGencodeGeneCardsHGNC
HPRDLynxMGIneXtProtPubMedUniProtKB
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 5.74 RPKM in Uterus
Total median expression: 128.11 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -144.20295-0.489 Picture PostScript Text
3' UTR -341.201707-0.200 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q4W4Y0
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein SequenceProtein Sequence   
AlignmentAlignmentAlignment   

-  Descriptions from all associated GenBank mRNAs
  JD460643 - Sequence 441667 from Patent EP1572962.
BC105030 - Homo sapiens chromosome 14 open reading frame 28, mRNA (cDNA clone MGC:132690 IMAGE:8144033), complete cds.
BC105032 - Homo sapiens chromosome 14 open reading frame 28, mRNA (cDNA clone MGC:132692 IMAGE:8144035), complete cds.
AF250395 - Homo sapiens dopamine receptor interacting protein 1 (DRIP1) mRNA, complete cds.
JD401301 - Sequence 382325 from Patent EP1572962.
JD066748 - Sequence 47772 from Patent EP1572962.
JD179590 - Sequence 160614 from Patent EP1572962.
JD103957 - Sequence 84981 from Patent EP1572962.
JD211251 - Sequence 192275 from Patent EP1572962.
AK126985 - Homo sapiens cDNA FLJ45039 fis, clone BRAWH3020318.
KJ895368 - Synthetic construct Homo sapiens clone ccsbBroadEn_04762 C14orf28 gene, encodes complete protein.
BC030258 - Homo sapiens, Similar to hypothetical gene LOC122525, clone IMAGE:4421196, mRNA, partial cds.
JD150977 - Sequence 132001 from Patent EP1572962.
JD503640 - Sequence 484664 from Patent EP1572962.
JD420661 - Sequence 401685 from Patent EP1572962.
JD265454 - Sequence 246478 from Patent EP1572962.
JD160646 - Sequence 141670 from Patent EP1572962.
JD348292 - Sequence 329316 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: CN028_HUMAN, DRIP1, ENST00000325192.1, ENST00000325192.2, ENST00000325192.3, ENST00000325192.4, ENST00000325192.5, ENST00000325192.6, ENST00000325192.7, NM_001017923, Q4W4Y0, uc001wvo.1, uc001wvo.2, uc001wvo.3, uc001wvo.4, uc001wvo.5
UCSC ID: ENST00000325192.8
RefSeq Accession: NM_001017923
Protein: Q4W4Y0 (aka CN028_HUMAN)
CCDS: CCDS32069.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.