Human Gene PIGL (ENST00000225609.10) from GENCODE V44
Description: Homo sapiens phosphatidylinositol glycan anchor biosynthesis class L (PIGL), mRNA. (from RefSeq NM_004278) RefSeq Summary (NM_004278): This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000225609.10 Gencode Gene: ENSG00000108474.17 Transcript (Including UTRs) Position: hg38 chr17:16,217,210-16,326,411 Size: 109,202 Total Exon Count: 7 Strand: + Coding Region Position: hg38 chr17:16,217,227-16,325,898 Size: 108,672 Coding Exon Count: 7
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9Y2B2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.