Human Gene KRT38 (ENST00000246646.4) from GENCODE V44
Description: Homo sapiens keratin 38 (KRT38), mRNA. (from RefSeq NM_006771) RefSeq Summary (NM_006771): The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000246646.4 Gencode Gene: ENSG00000171360.4 Transcript (Including UTRs) Position: hg38 chr17:41,436,154-41,440,983 Size: 4,830 Total Exon Count: 7 Strand: - Coding Region Position: hg38 chr17:41,437,412-41,440,921 Size: 3,510 Coding Exon Count: 7
ID:KRT38_HUMAN DESCRIPTION: RecName: Full=Keratin, type I cuticular Ha8; AltName: Full=Hair keratin, type I Ha8; AltName: Full=Keratin-38; Short=K38; MISCELLANEOUS: There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic). SIMILARITY: Belongs to the intermediate filament family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00038 - Intermediate filament protein
ModBase Predicted Comparative 3D Structure on O76015
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005198 structural molecule activity GO:0005515 protein binding