Human Gene MYNN (ENST00000349841.10) from GENCODE V44
Description: Homo sapiens myoneurin (MYNN), transcript variant 5, non-coding RNA. (from RefSeq NR_033703) RefSeq Summary (NM_018657): This gene encodes a member of the BTB/POZ and zinc finger domain-containing protein family that are involved in the control of gene expression. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 14. [provided by RefSeq, Jun 2010]. Gencode Transcript: ENST00000349841.10 Gencode Gene: ENSG00000085274.16 Transcript (Including UTRs) Position: hg38 chr3:169,773,396-169,789,716 Size: 16,321 Total Exon Count: 8 Strand: + Coding Region Position: hg38 chr3:169,774,296-169,786,678 Size: 12,383 Coding Exon Count: 7
ID:MYNN_HUMAN DESCRIPTION: RecName: Full=Myoneurin; AltName: Full=Zinc finger and BTB domain-containing protein 31; SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Mainly expressed in the neuromuscular system. Located in and around synaptic myonuclei in adult muscle. Expression is dysregulated after nerve injury. Also found in the testis, ovary and placenta. SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family. SIMILARITY: Contains 1 BTB (POZ) domain. SIMILARITY: Contains 8 C2H2-type zinc fingers.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NPC7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0003676 nucleic acid binding GO:0003677 DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0008270 zinc ion binding GO:0046872 metal ion binding
Biological Process: GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:1990830 cellular response to leukemia inhibitory factor