Human Gene TSC22D4 (ENST00000300181.7) from GENCODE V44
Description: Homo sapiens TSC22 domain family member 4 (TSC22D4), transcript variant 1, mRNA. (from RefSeq NM_030935) RefSeq Summary (NM_030935): TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3; MIM 300506) (Kester et al., 1999 [PubMed 10488076]; Fiorenza et al., 2001 [PubMed 11707329]).[supplied by OMIM, Mar 2008]. Gencode Transcript: ENST00000300181.7 Gencode Gene: ENSG00000166925.9 Transcript (Including UTRs) Position: hg38 chr7:100,466,519-100,479,214 Size: 12,696 Total Exon Count: 5 Strand: - Coding Region Position: hg38 chr7:100,466,959-100,478,038 Size: 11,080 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9Y3Q8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0005515 protein binding
Biological Process: GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0045892 negative regulation of transcription, DNA-templated GO:0070236 negative regulation of activation-induced cell death of T cells