Human Gene PTCHD1 (ENST00000379361.5) from GENCODE V44
Description: Homo sapiens patched domain containing 1 (PTCHD1), mRNA. (from RefSeq NM_173495) RefSeq Summary (NM_173495): This gene encodes a membrane protein with a patched domain. The encoded protein is similar to Drosophila proteins which act as receptors for the morphogen sonic hedgehog. Deletions in this gene, which is located on the X chromosome, are associated with intellectual disability and autism (PMID: 21091464, PMID: 20844286). [provided by RefSeq, Aug 2011]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Gencode Transcript: ENST00000379361.5 Gencode Gene: ENSG00000165186.12 Transcript (Including UTRs) Position: hg38 chrX:23,334,849-23,404,374 Size: 69,526 Total Exon Count: 3 Strand: + Coding Region Position: hg38 chrX:23,334,876-23,394,185 Size: 59,310 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
