Human Gene KRTAP21-3 (ENST00000444335.1) from GENCODE V44
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Sequence and Links to Tools and Databases
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Comments and Description Text from UniProtKB
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ID: KR213_HUMAN
DESCRIPTION: RecName: Full=Keratin-associated protein 21-3;
FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. SUBUNIT: Interacts with hair keratins (By similarity).
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Primer design for this transcript
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
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The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
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Protein Domain and Structure Information
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ModBase Predicted Comparative 3D Structure on Q3LHN1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
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Orthologous Genes in Other Species
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Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse | Rat | Zebrafish | D. melanogaster | C. elegans | S. cerevisiae |
No ortholog | No ortholog | No ortholog | No ortholog | No ortholog | No ortholog |
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Gene Ontology (GO) Annotations with Structured Vocabulary
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Descriptions from all associated GenBank mRNAs
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AB180042 - Homo sapiens KRTAP21-3 mRNA for keratin associated protein, complete cds.
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Biochemical and Signaling Pathways
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Other Names for This Gene
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Alternate Gene Symbols: KAP21.3, KR213_HUMAN, NM_001164435, Q3LHN1, uc021wii.1 UCSC ID: ENST00000444335.1 RefSeq Accession: NM_001164435
Protein: Q3LHN1
(aka KR213_HUMAN)
CCDS: CCDS54481.1
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Methods, Credits, and Use Restrictions
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Click here
for details on how this gene model was made and data restrictions if any.
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