Human Gene CAPG (ENST00000409670.5) from GENCODE V44
Description: Homo sapiens capping actin protein, gelsolin like (CAPG), transcript variant 2, mRNA. (from RefSeq NM_001256139) RefSeq Summary (NM_001256139): This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]. Gencode Transcript: ENST00000409670.5 Gencode Gene: ENSG00000042493.16 Transcript (Including UTRs) Position: hg38 chr2:85,394,828-85,414,042 Size: 19,215 Total Exon Count: 10 Strand: - Coding Region Position: hg38 chr2:85,394,893-85,402,145 Size: 7,253 Coding Exon Count: 9
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
