Human Gene CT45A5 (ENST00000487941.6) from GENCODE V44
  Description: Homo sapiens cancer/testis antigen family 45 member A5 (CT45A5), transcript variant 2, mRNA. (from RefSeq NM_001172288)
RefSeq Summary (NM_001172288): This gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer/testis (CT) family of antigens, and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014].
Gencode Transcript: ENST00000487941.6
Gencode Gene: ENSG00000228836.9
Transcript (Including UTRs)
   Position: hg38 chrX:135,777,130-135,785,298 Size: 8,169 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg38 chrX:135,777,636-135,781,729 Size: 4,094 Coding Exon Count: 4 

Page IndexSequence and LinksPrimersCTDMicroarray ExpressionRNA Structure
Other SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:135,777,130-135,785,298)mRNA (may differ from genome)Protein (189 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCLynxMalacardsMGIneXtProtOMIM
PubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -29.0085-0.341 Picture PostScript Text
3' UTR -124.90506-0.247 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
      
      
      
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  AK098689 - Homo sapiens cDNA FLJ25823 fis, clone TST07974.
JD349958 - Sequence 330982 from Patent EP1572962.
JD182286 - Sequence 163310 from Patent EP1572962.
JD154810 - Sequence 135834 from Patent EP1572962.
JD492972 - Sequence 473996 from Patent EP1572962.
JD409929 - Sequence 390953 from Patent EP1572962.
JD279792 - Sequence 260816 from Patent EP1572962.
JD359618 - Sequence 340642 from Patent EP1572962.
JD557065 - Sequence 538089 from Patent EP1572962.
JD344955 - Sequence 325979 from Patent EP1572962.
BC028711 - Homo sapiens cancer/testis antigen family 45, member A3, mRNA (cDNA clone MGC:27005 IMAGE:4828274), complete cds.
AY743709 - Homo sapiens cancer/testis antigen CT45-1 (CT45) mRNA, complete cds.
AY743710 - Homo sapiens cancer/testis antigen CT45-2 (CT45) mRNA, complete cds.
AY743711 - Homo sapiens cancer/testis antigen CT45-3 (CT45) mRNA, complete cds.
AY743714 - Homo sapiens cancer/testis antigen CT45-6 (CT45) mRNA, complete cds.
JD516901 - Sequence 497925 from Patent EP1572962.
BC140913 - Homo sapiens cancer/testis antigen family 45, member A1, mRNA (cDNA clone MGC:176590 IMAGE:9056725), complete cds.
BC140735 - Homo sapiens cancer/testis antigen family 45, member A3, mRNA (cDNA clone MGC:176412 IMAGE:9021603), complete cds.
BC140926 - Homo sapiens cancer/testis antigen family 45, member A3, mRNA (cDNA clone MGC:176603 IMAGE:9056738), complete cds.
BC144437 - Homo sapiens cancer/testis antigen family 45, member A3, mRNA (cDNA clone MGC:177976 IMAGE:9052959), complete cds.
JD171417 - Sequence 152441 from Patent EP1572962.
JD419781 - Sequence 400805 from Patent EP1572962.
JD452852 - Sequence 433876 from Patent EP1572962.
JD048803 - Sequence 29827 from Patent EP1572962.
CU688546 - Synthetic construct Homo sapiens gateway clone IMAGE:100020195 5' read CT45-3 mRNA.
HQ448322 - Synthetic construct Homo sapiens clone IMAGE:100071740; CCSB001506_01 cancer/testis antigen CT45-3 (RP13-36C9.3) gene, encodes complete protein.
KJ896287 - Synthetic construct Homo sapiens clone ccsbBroadEn_05681 CT45A3 gene, encodes complete protein.
DQ891584 - Synthetic construct clone IMAGE:100004214; FLH178360.01X; RZPDo839C04128D cancer/testis antigen CT45-2 (RP13-36C9.1) gene, encodes complete protein.
DQ894778 - Synthetic construct Homo sapiens clone IMAGE:100009238; FLH178356.01L; RZPDo839C04127D cancer/testis antigen CT45-2 (RP13-36C9.1) gene, encodes complete protein.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000487941.1, ENST00000487941.2, ENST00000487941.3, ENST00000487941.4, ENST00000487941.5, NM_001172288, P0DMU8, uc065bgc.1
UCSC ID: ENST00000487941.6
RefSeq Accession: NM_001172288
CCDS: CCDS35406.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.