Mouse Gene Chd7 (ENSMUST00000051558.10) from GENCODE VM33
Description: Mus musculus chromodomain helicase DNA binding protein 7 (Chd7), transcript variant 2, mRNA. (from RefSeq NM_001355382) RefSeq Summary (NM_001277149): This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Gencode Transcript: ENSMUST00000051558.10 Gencode Gene: ENSMUSG00000041235.13 Transcript (Including UTRs) Position: mm39 chr4:8,691,365-8,867,659 Size: 176,295 Total Exon Count: 38 Strand: + Coding Region Position: mm39 chr4:8,751,505-8,866,655 Size: 115,151 Coding Exon Count: 37
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on A2AJK6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
