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Rap1 ⊣ extracellular signal regulated kinase 1/2: " T-cell receptor (TCR)-CD3/CD28 mediated activation of Rap1 and Akt was retained in Tregs, but activation of Ras, mitogenactivated protein kinase 1/2 ( MEK1/2 ), and extracellular signal regulated kinase 1/2 ( Erk1/2 ) was impaired "
Akt ⊣ mitogenactivated protein kinase 1/2: " T-cell receptor (TCR)-CD3/CD28 mediated activation of Rap1 and Akt was retained in Tregs, but activation of Ras, mitogenactivated protein kinase 1/2 ( MEK1/2 ), and extracellular signal regulated kinase 1/2 ( Erk1/2 ) was impaired "
Akt ⊣ extracellular signal regulated kinase 1/2: " T-cell receptor (TCR)-CD3/CD28 mediated activation of Rap1 and Akt was retained in Tregs, but activation of Ras, mitogenactivated protein kinase 1/2 ( MEK1/2 ), and extracellular signal regulated kinase 1/2 ( Erk1/2 ) was impaired "
Rap1 → (TCR)-CD3/CD28: " T-cell receptor (TCR)-CD3/CD28 mediated activation of Rap1 and Akt was retained in Tregs, but activation of Ras, mitogenactivated protein kinase 1/2 ( MEK1/2 ), and extracellular signal regulated kinase 1/2 ( Erk1/2 ) was impaired "
Rap1 → T-cell receptor (TCR)-CD3/CD28: " T-cell receptor (TCR)-CD3/CD28 mediated activation of Rap1 and Akt was retained in Tregs, but activation of Ras, mitogenactivated protein kinase 1/2 ( MEK1/2 ), and extracellular signal regulated kinase 1/2 ( Erk1/2 ) was impaired "
Akt → (TCR)-CD3/CD28: " T-cell receptor (TCR)-CD3/CD28 mediated activation of Rap1 and Akt was retained in Tregs, but activation of Ras, mitogenactivated protein kinase 1/2 ( MEK1/2 ), and extracellular signal regulated kinase 1/2 ( Erk1/2 ) was impaired "
Akt → T-cell receptor (TCR)-CD3/CD28: " T-cell receptor (TCR)-CD3/CD28 mediated activation of Rap1 and Akt was retained in Tregs, but activation of Ras, mitogenactivated protein kinase 1/2 ( MEK1/2 ), and extracellular signal regulated kinase 1/2 ( Erk1/2 ) was impaired "
cyclin dependent kinase ⊣ p27kip1: " Tregs were blocked from cell cycle progression due to decrease of cyclin E and cyclin A and increase of p27kip1 ( p27kip cyclin dependent kinase inhibitor ) "
p27kip1 ⊣ IL-2: " IL-2 induced sustained increase of cyclin E and cyclin A and prevented up-regulation of p27kip1 "
p27kip1 ⊣ IL-2: " IL-2 induced sustained increase of cyclin E and cyclin A and prevented up-regulation of p27kip1 "