Gene interactions and pathways from curated databases and text-mining
Appl Environ Microbiol 2007, PMID: 17905884

Nisin-controlled extracellular production of interleukin-2 in Lactococcus lactis strains, without the requirement for a signal peptide sequence.

Fernández, Antonio; Rodríguez, Juan M; Bongaerts, Roy J; Gasson, Michael J; Horn, Nikki

Secretion of the cytokine interleukin-2 (IL-2) was investigated in Lactococcus lactis using the secretory machinery of the bacteriocin lactococcin A. Surprisingly, the lcnCD transport genes were not essential for mouse IL-2 secretion. Furthermore, expression of a mature mouse IL-2 gene resulted in interleukin secretion without the requirement for a leader sequence.

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Text Mining Data

interleukin ⊣ IL-2: " Furthermore, expression of a mature mouse IL-2 gene resulted in interleukin secretion without the requirement for a leader sequence "

Manually curated Databases

No curated data.