Gene interactions and pathways from curated databases and text-mining
PloS one 2013, PMID: 23383273

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

Yu, Cheng-Chou; Yang, Jyh-Chin; Chang, Yen-Ching; Chuang, Jiing-Guang; Lin, Chung-Wu; Wu, Ming-Shiang; Chow, Lu-Ping

Previous studies have demonstrated that valosin-containing protein (VCP) is associated with H. pylori-induced gastric carcinogenesis. By identifying the interactome of VCP overexpressed in AGS cells using a subtractive proteomics approach, we aimed to characterize the cellular responses mediated by VCP and its functional roles in H. pylori-associated gastric cancer. VCP immunoprecipitations followed by proteomic analysis identified 288 putative interacting proteins, 18 VCP-binding proteins belonged to the PI3K/Akt signaling pathway. H. pylori infection increased the interaction between Akt and VCP, Akt-dependent phosphorylation of VCP, levels of ubiquitinated proteins, and aggresome formation in AGS cells. Furthermore, phosphorylated VCP co-localized with the aggresome, bound ubiquitinated proteins, and increased the degradation of cellular regulators to protect H. pylori-infected AGS cells from apoptosis. Our study demonstrates that VCP phosphorylation following H. pylori infection promotes both gastric epithelial cell survival, mediated by the PI3K/Akt pathway, and the degradation of cellular regulators. These findings provide novel insights into the mechanisms of H. pylori infection induced gastric carcinogenesis.

Diseases/Pathways annotated by Medline MESH: Helicobacter Infections
Document information provided by NCBI PubMed

Text Mining Data

VCP → Akt: " H. pylori infection increased the interaction between Akt and VCP, Akt dependent phosphorylation of VCP , levels of ubiquitinated proteins, and aggresome formation in AGS cells "

Manually curated Databases

  • IRef Biogrid Interaction: VCP — UBXN6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HSPA8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HTT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HSP90AA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — FAF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SUMO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SUMO2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — UBQLN1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — KIAA1468 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — DYNC1LI1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CTNNA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARIH1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TAX1BP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COG5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COPS7A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TMEM33 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FHOD1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — GTF3C5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — EIF4A2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCDC134 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CHEK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — GTF3C3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CANX (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PDCD6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RNF7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — YWHAB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CAB39 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DOCK7 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — AP2A2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCT6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CSK — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: UBR4 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GOLPH3L — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BCLAF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — G3BP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: EIF5A — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TUBGCP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NUP62 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PKM (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LYAR — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RNF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RABGAP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TOM1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HSPB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HSBP1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — MTOR (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SAP18 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ST13 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TRIM21 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RRP12 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RAF1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BCCIP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — LRIG1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDK4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — WRNIP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FKBP15 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PDCD10 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — GGA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TTC4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — KDM3B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PIK3R2 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NCDN (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NAPA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HSPE1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — KIAA1524 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — STMN1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — UBE2S (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HAUS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — APPL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CNOT2 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NEK2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ANXA2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — UBE2M (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — AP1B1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ACTN1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PTPN9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ACACA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ARFGAP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RAB11B — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RPN1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDKN1B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCDC132 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CENPH (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COMMD6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ALDH18A1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCT5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — YWHAE (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PKN2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RIF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TOP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HELLS (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TSG101 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RBM23 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CCT8 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — DYNC1I2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NFKB2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CIDEC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BAG2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COIL (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TMED10 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CLASP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PPP6C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — POLR2B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ULK3 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YWHAQ — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ARHGAP17 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ARPC2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SDCCAG3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COMMD1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDKN2AIP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BID (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDC27 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SLC3A2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HUWE1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TNKS1BP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SUPT16H (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — GBF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NUP107 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SPC24 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CNOT8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CSNK2B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — MARK2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RAB14 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CASP9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — FERMT2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — KIAA1279 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RPL6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RBFOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HSPA1A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SMARCC1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SEC22B — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COPS3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PDCD4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BAIAP2L1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HNRNPH2 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — MAPK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — DUSP9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — MAPK3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HS1BP3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HNRNPH3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BSG (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — YWHAG (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ARFGEF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BAX (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PNO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NUP205 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CEP55 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ADCK3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ARF6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — VCL (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CASP7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RAB7A — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — DIAPH3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ICK (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PRKAR2A — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RAB3GAP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ADD1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CUL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VIM — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ANAPC7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDC42EP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — GET4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BZW2 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NCAPH — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HEATR1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — UBB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TCP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PIK3C2B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: C11orf82 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — KCMF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TELO2 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TRIP12 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SEC16A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CDKN1A — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SPAST (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SCFD1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RQCD1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TNPO3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BAG6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COG4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — INF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NME2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CUL7 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WDR43 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — USP10 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — COPE (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HDLBP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RFC5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RPS9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — DSP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CDC42EP4 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ZFR (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — GGA2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ANXA5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NBEA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ANXA7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PTPN23 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SON (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDC37 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTB — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SNX3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ATXN10 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HIP1R — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HOOK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — UBA5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — STAT1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — WNK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MDN1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ARHGEF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TP53 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MAPK13 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SKP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SRSF11 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — VPS53 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RSU1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — VIL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CTNND1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — C3orf17 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PDXDC1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GTF3C1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: UBR5 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — IQCB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CAAP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCT2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — MDM2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARIH2 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCNB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TBC1D10B — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: COMT — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PPP2CB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ANKHD1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SESN2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WDR82 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — H2AFJ (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RNF126 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CNOT10 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HNRNPA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TP53BP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CDK2AP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — LMNB2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BAD — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TBC1D9B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HSPA5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ESPL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TTK (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCT7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TAF6L (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RFC3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NUPL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ALS2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CCT4 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — YWHAH (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PLK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — BRAT1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TERF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PRKAG1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AKT1 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — LMNA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — SMARCA5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — DNM3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CTNNBL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: POLR3C — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ZNF326 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — TRIM25 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RAB10 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — MAP7D3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — CCT3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — FANCI (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — HSP90AB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NMD3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — RAB3GAP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — MAP2K1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RPS13 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — STAG2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SRSF3 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — PLEC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NUMA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HSPA4 — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AMFR — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ASPSCR1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YWHAZ — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — UBC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — VCP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — NFKBIA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: VCP — ATXN3 (physical association, affinity chromatography technology)
In total, 287 gene pairs are associated to this article in curated databases