Gene interactions and pathways from curated databases and text-mining
SMC3: top 25 interacting genes (chr10:112327448-112364392)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SMC3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with SMC3, not among the Top 25
Other genes interacting with SMC3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK13 ▸ MAPK12 ▸ MAPK15 ▸ IL4 ▸ MAPK4 ▸ MAPK11 ▸ MAPK1 ▸
MAPK14 ▸ MAPK7 ▸ MAPK8 ▸ MAPK10 ▸ NOS2 ▸ MAPK9 ▸ RHOA ▸
MAPK6 ▸ MAPK3 ▸ MMP24 ▸ MMP25 ▸ MMP15 ▸ MMP3 ▸ ROCK1 ▸
MMP20 ▸ MMP21 ▸ CCL2 ▸ IFNG ▸ MMP19 ▸ IL1A ▸ MMP26 ▸
MMP14 ▸ JUN ▸ BRCA1 ▸ MMP1 ▸ PDGFRB ▸ MMP11 ▸ MMP10 ▸
MMP8 ▸ MMP7 ▸ MMP17 ▸ IRF6 ▸ MMP28 ▸ MMP16 ▸ GH1 ▸
MMP27 ▸ MMP13 ▸ MMP12 ▸ CFP ▸ PAPPA ▸ S1PR2 ▸ IL6 ▸
EGR1 ▸ TCF7 ▸ ROCK2 ▸ KLF4 ▸ CA2 ▸ TGFB2 ▸ ERBB2 ▸
FOS ▸ TCF4 ▸ TCF23 ▸ RETN ▸ SMAD7 ▸ IL10 ▸ PDGFD ▸
CHKA ▸ TCF3 ▸ LPA ▸ TCF25 ▸ TCF24 ▸ PDGFRA ▸ MYBL2 ▸
FGFR3 ▸ BIRC2 ▸ TCF12 ▸ FGF1 ▸ TCF19 ▸ PTPN11 ▸ TCF20 ▸
TGFB3 ▸ KLF5 ▸ VEGFA ▸ TCF21 ▸ GPI ▸ IL3 ▸ TCF15 ▸
PAFAH1B1 ▸ CAD ▸ MYCBP2 ▸ LZTR1 ▸ RBM39 ▸ TBK1 ▸ TRABD ▸
RCN2 ▸ CCDC85C ▸ S100A11 ▸ RAB7A ▸ PPP2CA ▸ BAG6 ▸ HIST1H3H ▸
DNAJB1 ▸ CENPT ▸ RPN1 ▸ TUBB6 ▸ CHD6 ▸ MLF2 ▸ VWA9 ▸
RUNX1 ▸ TUBB4B ▸ CBS ▸ SKA2 ▸ CALU ▸ CEBPZ ▸ SEC16A ▸
CLPP ▸ SKA1 ▸ SLC7A5 ▸ ATG4B ▸ TPR ▸ CDCA8 ▸ MDM1 ▸
NFATC4 ▸ SNX18 ▸ RBM22 ▸ USP13 ▸ CSNK2B ▸ TRAF3IP1 ▸ EIF2S1 ▸
MCM6 ▸ EXOSC3 ▸ WDR33 ▸ SLC25A19 ▸ STAU1 ▸ AKAP8 ▸ PDS5B ▸
TUBA1A ▸ CDK2 ▸ CIRH1A ▸ RHBDD2 ▸ TPM4 ▸ PARP1 ▸ MSH6 ▸
DHX30 ▸ SLC39A7 ▸ PAXIP1 ▸ HIST1H1A ▸ SLC25A11 ▸ SLC25A4 ▸ NDUFA8 ▸
HIST1H3E ▸ KPNB1 ▸ HNRNPU ▸ ESCO1 ▸ AFG3L2 ▸ SON ▸ CENPM ▸
BAG2 ▸ NUP205 ▸ WDR36 ▸ PAXBP1 ▸ RPS23 ▸ TECR ▸ NUP37 ▸
KPNA2 ▸ LAGE3 ▸ NUP153 ▸ TMPO ▸ SLC25A22 ▸ SLC1A5 ▸ TARS2 ▸
LUC7L ▸ RPLP0 ▸ HIGD1A ▸ IMMT ▸ SPC24 ▸ RCOR2 ▸ RIF1 ▸
SF3B3 ▸ PRKAA2 ▸ SMC4 ▸ PGAM5 ▸ RPL18 ▸ HIST1H3F ▸ POLRMT ▸
HSPA2 ▸ SYCP2 ▸ PRKAG1 ▸ CEPT1 ▸ C1QBP ▸ HIST1H2AH ▸ TINF2 ▸
RANBP2 ▸ EIF3H ▸ C19orf70 ▸ EMD ▸ HJURP ▸ CHEK2 ▸ FBL ▸
HIST1H2AC ▸ HSPA4L ▸ RPLP1 ▸ RRP1B ▸ EIF6 ▸ C7orf50 ▸ DIDO1 ▸
PELO ▸ CLU ▸ COPS6 ▸ STAG3 ▸ UBE2S ▸ DDX21 ▸ ZNF326 ▸
CCT3 ▸ HIST1H3B ▸ CENPC ▸ SDF4 ▸ AKAP8L ▸ ATM ▸ HDAC9 ▸
HORMAD1 ▸ RASSF8 ▸ NEK4 ▸ SSX10 ▸ UTP18 ▸ YWHAQ ▸ CEP192 ▸
PWP2 ▸ SMARCA5 ▸ RAB1B ▸ KDELR2 ▸ SLC3A2 ▸ DNAJA1 ▸ YLPM1 ▸
RPL7 ▸ ATP5C1 ▸ SDCCAG3 ▸ SLC25A42 ▸ USP7 ▸ HDAC8 ▸ RCN1 ▸
LETM1 ▸ HDAC2 ▸ PHIP ▸ C7orf26 ▸ CAMKK2 ▸ RPL32 ▸ YWHAE ▸
STAG1 ▸ HDGF ▸ NCL ▸ ATXN10 ▸ RFC1 ▸ MDH2 ▸ GFPT2 ▸
MAT2A ▸ PPAN ▸ PLEKHG1 ▸ ZMYM2 ▸ RPL35 ▸ SLC25A6 ▸ SYNE1 ▸
DNAJA4 ▸ BUB3 ▸ DSN1 ▸ C8orf33 ▸ DZIP3 ▸ CLPB ▸ ASPH ▸
TIMM23 ▸ TPM3 ▸ RPL19 ▸ USMG5 ▸ HSPH1 ▸ CPNE3 ▸ PABPC1 ▸
RCC2 ▸ FLNC ▸ KDM1A ▸ RB1 ▸ SRSF2 ▸ WDR5 ▸ ACACB ▸
RSL1D1 ▸ CPT1A ▸ CROCC ▸ MDN1 ▸ ACOT8 ▸ MXD3 ▸ CLASP2 ▸
CENPO ▸ COPA ▸ PRPF8 ▸ SUN2 ▸ TP53BP2 ▸ GEMIN5 ▸ METTL21B ▸
NUP85 ▸ ERCC6L ▸ ZC3HAV1 ▸ SIN3A ▸ NRBF2 ▸ SMC1B ▸ CHCHD3 ▸
CHD3 ▸ FBXO25 ▸ APC ▸ UFD1L ▸ BIRC5 ▸ AIRE ▸ ZSCAN2 ▸
RPL23 ▸ SSR1 ▸ CENPN ▸ LMNA ▸ NUP93 ▸ PHC2 ▸ PHC3 ▸
CUL2 ▸ MAGED2 ▸ C2orf47 ▸ INCENP ▸ MCM3 ▸ KIF3B ▸ THRAP3 ▸
RBM14 ▸ STAG2 ▸ GEMIN4 ▸ SNRPD1 ▸ FAF2 ▸ KCTD3 ▸ CDC45 ▸
KIF2A ▸ TRIM28 ▸ SUN1 ▸ TRAFD1 ▸ FER ▸ NSMCE2 ▸ PSMD3 ▸
TUBB3 ▸ BDH1 ▸ IK ▸ RPL35A ▸ CENPH ▸ THOC2 ▸ POT1 ▸
CDCA5 ▸ MTA2 ▸ TIMM13 ▸ SOX2 ▸ SLC25A5 ▸ MCM2 ▸ IARS ▸
CKAP5 ▸ SRSF5 ▸ PPP1R12A ▸ ZWILCH ▸ MTHFD2 ▸ GANAB ▸ ATP5A1 ▸
DNAJB2 ▸ HADHA ▸ EXOSC10 ▸ SMC2 ▸ RFC2 ▸ ATP1A1 ▸ SGOL1 ▸
FAM175B ▸ PPA1 ▸ SNW1 ▸ PDCD11 ▸ SCO2 ▸ YWHAB ▸ RANGAP1 ▸
GYS1 ▸ PRKDC ▸ ATG2B ▸ NDE1 ▸ ASAP1 ▸ RPS7 ▸ IRS4 ▸
RPS15A ▸ SNRPD3 ▸ AGPS ▸ KCTD10 ▸ CENPK ▸ CDK8 ▸ EEF2 ▸
MYBBP1A ▸ DNAJB11 ▸ HAX1 ▸ RPN2 ▸ COPB1 ▸ DKC1 ▸ DNTTIP2 ▸
POLR2B ▸ PDS5A ▸ KNTC1 ▸ ZW10 ▸ XPO5 ▸ TUBA1C ▸ MXD1 ▸
CFL1 ▸ BUB1 ▸ MAD2L1 ▸ PPP6R1 ▸ CANX ▸ CYB5R3 ▸ MGME1 ▸
NUP43 ▸ RNF17 ▸ ATAD2 ▸ HDAC1 ▸ HIST1H3D ▸ PHB2 ▸ LYPLAL1 ▸
ALYREF ▸ PCBP2 ▸ NASP ▸ NEK6 ▸ KIAA0368 ▸ PTPLAD1 ▸ TERF2IP ▸
BRCA2 ▸ FLNA ▸ ZFR ▸ RAD21L1 ▸ SEC61B ▸ SPTLC1 ▸ AIFM1 ▸
CUL3 ▸ SPDL1 ▸ NUP160 ▸ LRRC59 ▸ NUP107 ▸ TSR1 ▸ CCNB2 ▸
ALG1 ▸ VDAC1 ▸ RPL5 ▸ KIAA0226 ▸ CCT5 ▸ IQGAP2 ▸ SFN ▸
SLC25A3 ▸ HIST1H3J ▸ ITCH ▸ NUF2 ▸ GNL3 ▸ CENPE ▸ CLN6 ▸
LCN1P1 ▸ CSNK2A1 ▸ UBL4A ▸ DICER1 ▸ SRSF1 ▸ EIF5B ▸ DPM1 ▸
UBC ▸ AURKB ▸ RUVBL2 ▸ ASF1A ▸ SRSF7 ▸ RNF20 ▸ ATP5J2 ▸
WDR74 ▸ POLDIP3 ▸ DNAJB6 ▸ CASP4 ▸ RPL6 ▸ FAM115A ▸ CSNK2A2 ▸
POLR2H ▸ ERLIN2 ▸ DDX47 ▸ GCFC2 ▸ MXI1 ▸ SPC25 ▸ COPG2 ▸
YWHAG ▸ CDC5L ▸ VCP ▸ GSPT1 ▸ ATP2A3 ▸ YWHAZ ▸ EIF3I ▸
MTMR3 ▸ LCN1 ▸ ADD3 ▸ H1FX ▸ TMOD3 ▸ CCT8 ▸ CENPU ▸
STAMBPL1 ▸ PSMC2 ▸ CBX4 ▸ PPP2R5C ▸ SYCE2 ▸ KIF2C ▸ CCDC158 ▸
RANBP9 ▸ TBC1D7 ▸ RAE1 ▸ SSU72 ▸ CCT2 ▸ ADRM1 ▸ KHDRBS2 ▸
PSIP1 ▸ IGF2BP3 ▸ SYCE1 ▸ UTP6 ▸ BMI1 ▸ AMBRA1 ▸ OGDH ▸
PPP6R2 ▸ DHX9 ▸ ALDH3A2 ▸ CENPA ▸ HEATR1 ▸ MCMBP ▸ MRTO4 ▸
MTA1 ▸ TFDP1 ▸ TMEM33 ▸ ESCO2 ▸ PNN ▸ CDC42EP1 ▸ RING1 ▸
TOMM70A ▸ CLIP1 ▸ CYLD ▸ ACIN1 ▸ POLR2A ▸ RBM12B-AS1 ▸ SUPT5H ▸
HIST1H1E ▸ TRIM41 ▸ RPL9 ▸ CTPS1 ▸ ADNP ▸ ATRX ▸ ANKRD44 ▸
CENPL ▸ TCEB1 ▸ NACA ▸ KIF3A ▸ TSC1 ▸ COPS5 ▸ LARS ▸
CCDC63 ▸ HNRNPF ▸ NUP98 ▸ RNF8 ▸ CHD4 ▸ TIMM50 ▸ BAZ1A ▸
EIF2S3 ▸ HIST3H3 ▸ WFDC5 ▸ HHIP ▸ ETV5 ▸ RNF219 ▸ PIK3R4 ▸
FOXK1 ▸ HIST1H3I ▸ MT-CO2 ▸ SEC13 ▸ NDC80 ▸ SRRM1 ▸ MXD4 ▸
MAPRE1 ▸ DDX6 ▸ RNF2 ▸ RUVBL1 ▸ HNRNPH1 ▸ TBKBP1 ▸ CENPQ ▸
UBD ▸ ERP44 ▸ TMED10 ▸ RBBP7 ▸ DDX17 ▸ HDAC5 ▸ HIST1H2BK ▸
PRPF6 ▸ TUBB2B ▸ SLC2A1 ▸ GTF3C1 ▸ IFIH1 ▸ TCP1 ▸ NIPBL ▸
CDIPT ▸ TOP2A ▸ MISP ▸ SF3A1 ▸ WAPAL ▸ GTF3C6 ▸ EPS8 ▸
DDB1 ▸ STAT1 ▸ BMS1 ▸ MOV10 ▸ DDX20 ▸ DISC1 ▸ ASUN ▸
DNAJA2 ▸ PPP6R3 ▸ ZNF546 ▸ NUDC ▸ RARS ▸ MCC ▸ ANKRD28 ▸
SF3B2 ▸ KIF18A ▸ MCM4 ▸ TRAP1 ▸ B9D2 ▸ DDX1 ▸ RPL22 ▸
STAT2 ▸ PCNA ▸ TUBB ▸ SEC61A1 ▸ FIP1L1 ▸ PLK2 ▸ SPECC1 ▸
MECP2 ▸ RBBP4 ▸ GEMIN2 ▸ NUP133 ▸ SRRM2 ▸ PES1 ▸ SSRP1 ▸
XRCC5 ▸ PI4KA ▸ YBX3 ▸ RPL29 ▸ NPLOC4 ▸ SUGT1 ▸ IKZF1 ▸
SMC1A ▸ SSR4 ▸ CALM1 ▸ CDC20 ▸ ESYT2 ▸ OBSL1 ▸ PPP1R9A ▸
SLC25A21 ▸ MAGED1 ▸ SLC25A10 ▸ SMN1 ▸ CENPF ▸ GCN1L1 ▸ PMS1 ▸
GATAD2A ▸ CENPP ▸ E2F2 ▸ KRI1 ▸ KIFAP3 ▸ HMGA1 ▸ FEZ1 ▸
RCC1 ▸ SUB1 ▸ STT3A ▸ TIMMDC1 ▸ HLA-B ▸ SDF2L1 ▸ MARS ▸
TFIP11 ▸ FARSB ▸ GLUD1 ▸ PPP1CC ▸ RPL24 ▸ TOMM22 ▸ LMNB1 ▸
TUBA1B ▸ EXOSC6 ▸ SLC25A13 ▸ CTCF ▸ NSL1 ▸ MBD3 ▸ DIMT1 ▸
CCNB1 ▸ SLC27A4 ▸ DDX5 ▸ TPX2 ▸ RBM34 ▸ SYNE2 ▸ AGK ▸
PIK3C3 ▸ TUBB4A ▸ INTS10 ▸ IMPDH2 ▸ PMF1 ▸ CCT4 ▸ CEP162 ▸
FAR1 ▸ BCLAF1 ▸ PSMC5 ▸ SLC25A12 ▸ STUB1 ▸ HSPA4 ▸ DDX27 ▸
PML ▸ YWHAH ▸ BECN1 ▸ RAD21 ▸ TP53 ▸ RBM28 ▸ UVRAG ▸
SRSF3 ▸ MIS12 ▸ HSPBP1 ▸ PCGF6 ▸ PLK1 ▸ SVIL ▸ ATP2A2 ▸
U2AF1 ▸ MCM7 ▸ USP10 ▸ HSD17B12 ▸ CLASP1 ▸ PPM1A ▸ HECTD1 ▸
RFC5 ▸ OSGEP ▸ MME ▸ MAU2 ▸ CASC5 ▸ EBNA1BP2 ▸ MAD1L1 ▸
PCGF2 ▸ SLC25A1 ▸ TERF1 ▸ GTPBP1 ▸ RRP12 ▸ SYCP1 ▸ RPL17 ▸
SFPQ ▸ WDR6 ▸ SRPK1 ▸ RPS27 ▸ ZWINT ▸ RPL13 ▸ CEP63 ▸
SLC25A33 ▸ SMN2 ▸ TTF2 ▸ FOXK2 ▸ CCT6A ▸ PGRMC1 ▸ MMS19 ▸
SMARCAD1 ▸ DNAJA3 ▸ IPO7 ▸ CACYBP ▸ CAND1 ▸ FBF1 ▸ NDUFA4 ▸
WRNIP1 ▸ EIF3B ▸ CDK1 ▸ NOL6 ▸ FANCI ▸ DIABLO ▸ TTC27 ▸
SDHA ▸ CENPI ▸ EXOSC2 ▸ GTF3C3 ▸ YBX2 ▸ ARHGEF2 ▸ XRCC6 ▸
RPS11 ▸ FAM193A ▸ KIAA0226L ▸ SLC16A1 ▸ AP1G1 ▸ PHC1 ▸ XAB2 ▸
HIST1H4A ▸ TOP1 ▸ RPL21 ▸ NOP2 ▸ EFTUD2 ▸ WRAP73 ▸ SMG1 ▸
XPO1 ▸ ATG14 ▸ SUMO2 ▸ CLPX ▸ STIP1 ▸ GRWD1 ▸ SHKBP1 ▸
GCDH ▸ CHD7 ▸ SNRPF ▸ ADAR ▸ BAZ1B ▸ SRPRB ▸ HIST1H3A ▸
TEX12 ▸ PPP6C ▸ ZC3H11A ▸ PPP2R5E ▸ DHX15 ▸ MKI67 ▸ SNRPB ▸
FEZ2 ▸ OSBPL8 ▸ MCM5 ▸ PHB ▸ HIST1H2BO ▸ XPOT ▸ SSR3 ▸
RFC3 ▸ RPL31 ▸ NDEL1 ▸ BUB1B ▸ TAOK1 ▸ PHKG2 ▸ ESPL1 ▸
MDM2 ▸ ATAD3A ▸ EPRS ▸ FKBP6 ▸ NEDD8 ▸ UTP14A ▸ DDX50 ▸
SF3B6 ▸ TERF2 ▸ ABCF1 ▸ HNRNPA3 ▸ POLDIP2 ▸ DARS ▸ APITD1 ▸
DDOST ▸ KPNA6 ▸ CCAR2 ▸ HYOU1 ▸ PPP1R9B ▸ ATP5O ▸ NOP56 ▸
HNRNPM ▸ PTOV1 ▸ MBD2 ▸ RFC4 ▸ RPGR ▸ KIF2B ▸ RPL34 ▸
ITGB3BP ▸ MCCC2 ▸ HUWE1 ▸ NUMA1 ▸ CDK4 ▸ FKBP8 ▸ SUPT16H ▸
HIST1H3G ▸ WDHD1 ▸ MYC ▸ RPL3 ▸ HDAC11 ▸ GTF3C5 ▸ SEC22B ▸
BRIX1 ▸ SEH1L ▸ FBXO6 ▸ NDUFA10 ▸ SGOL2 ▸ UBE2I ▸ HIST1H3C ▸
ERCC6 ▸
Data information
Please see the Gene Interactions Track Manual.