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CLCN3 — IL4
Text-mined interactions from Literome
Han et al., Laryngoscope 2006
(Rhinitis, Allergic, Perennial) :
After exposure to SB203580,
CLC-3 expression
induced by
IL-4 was downregulated in HNECs in a concentration and time dependent manner ... These results confirmed that
IL-4 can
induce CLC-3 production in HNECs with AR through a p38 MAPK dependent pathway
Li et al., Am J Rhinol 2007
(Chronic Disease...) :
Possible
role of transforming growth factor beta and
interleukin-4 in the up-regulation of CLC-2 and
CLC-3 in chronic rhinosinusitis ... The aim of this study was to evaluate the expression of chloride channel protein CLC-2 and CLC-3 in CRS without nasal polyps ( CRSsNP ) and evaluate the
roles of
interleukin (IL)-4 and transforming growth factor ( TGF ) beta in the up-regulation of CLC-2 and
CLC-3