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CD2 — NANOG
Text-mined interactions from Literome
Pan et al., J Biol Chem 2005
:
Paradoxically, whereas the removal of
CD2 reduced
NANOG activity by approximately 30-70 %, the removal of WR not only did not diminish but actually enhanced its activity by approximately 50-100 % depending on the cell lines analyzed ... These data suggest that either WR or
CD2 is
sufficient for
NANOG to function as a transactivator
Wang et al., J Biol Chem 2008
:
Here we demonstrate that
CD2 is
required for
Nanog to mediate ES cell self-renewal