Gene interactions and pathways from curated databases and text-mining

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CD2 — NANOG

Text-mined interactions from Literome

Pan et al., J Biol Chem 2005 : Paradoxically, whereas the removal of CD2 reduced NANOG activity by approximately 30-70 %, the removal of WR not only did not diminish but actually enhanced its activity by approximately 50-100 % depending on the cell lines analyzed ... These data suggest that either WR or CD2 is sufficient for NANOG to function as a transactivator
Wang et al., J Biol Chem 2008 : Here we demonstrate that CD2 is required for Nanog to mediate ES cell self-renewal