Gene interactions and pathways from curated databases and text-mining

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IFNG — PARK2

Text-mined interactions from Literome

Oda et al., Life Sci 1999 : Stimulation of PPD-specific and Der f-specific T cell lines with relevant antigens resulted in production of mostly interferon (IFN)-gamma and of interleukin (IL)-4 and IL-5, respectively
Salem et al., Int Arch Allergy Immunol 2000 (Hypersensitivity, Delayed...) : The analysis of production and gene expression of cytokines by DLN cells demonstrated that E2 treatment suppressed IL-2 and IFN-gamma production in response to PPD in vitro
Koga et al., Eur J Dermatol 2001 (Erythema Induratum...) : The patient 's peripheral blood mononuclear cells showed a high proliferation and produced interferon-gamma (IFN-gamma) in response to purified protein derivative (PPD)
Greinert et al., J Clin Immunol 2000 (Lung Diseases...) : For a subgroup of tuberculin skin test positive NTM patients we found significantly lower PPD induced IFN-gamma releases in cultured DWB ( P < 0.0002 ) and PBMC ( P < 0.0004 ) compared to MTb patients ... The four NTM patients with poor PPD induced IFN-gamma response hardly showed increased cytokine production on stimulation with their specific mycobacterium
Kamal et al., Clin Exp Allergy 2001 : In addition, Ac2-26 and dexamethasone inhibited Der p-induced IL-5 release and PPD induced IFN-gamma release in a concentration dependent fashion
Mochida-Nishimura et al., Cell Immunol 2001 : Both GM-Mphis and M-Mphis equally suppressed lymphocyte proliferation, but only M-Mphis suppressed IFN-gamma production in response to purified protein derivative (PPD)
Barth et al., Clin Exp Immunol 2003 (Hypersensitivity, Delayed...) : Active immunization of subject A with TT at the end of the observation period of 12 months resulted in a transient shift from type 1- to a mixed type 1/type 2-profile ( simultaneous PPD induced IFN-gamma- and TT-induced IL-5 production )
Brock et al., Am J Respir Crit Care Med 2004 (Tuberculosis) : This test measures the production of IFN-gamma in whole blood upon stimulation with purified protein derivative (PPD)
Yentür et al., J Neuroimmunol 2005 (Subacute Sclerosing Panencephalitis) : Proliferation, as well as IFN-gamma , IL-12 and IL-10 production in response to purified protein derivate (PPD) was impaired in SSPE patients
Okano et al., Immunology 2006 : Furthermore, PGE2 and EP2 receptor agonist significantly inhibited interleukin-5 and interferon-gamma production by peripheral blood mononuclear cells in response to Cry j 1 and PPD stimulation, respectively
Moormann et al., J Infect Dis 2007 (Burkitt Lymphoma...) : In contrast, IFN- gamma responses to PHA, PPD , and Plasmodium falciparum MSP-1 peptides did not significantly differ by age
McIlleron et al., Tuberculosis (Edinb) 2007 (Tuberculosis, Pulmonary) : In multivariate analysis of parameters at 2 months the strongest positive associations with disease free survival were IFN-gamma response to PPD ( p=0.002 ) and serum creatinine ( p=0.001 )
Eum et al., Diagn Microbiol Infect Dis 2008 (Tuberculosis) : We also examined the correlation between the interferon (IFN)-gamma response to these antigens and the exposure risk to TB by evaluating antigen-specific IFN-gamma release in comparison with IFN-gamma release in response to purified protein derivative (PPD) in 3 groups : medical students, nurses in a TB hospital, and TB patients
Elliott et al., J Infect Dis 2009 (HIV Infections...) : Raw IFN-gamma responses to RD1 antigens and PPD corrected for pre-ART CD4 ( + ) T cell counts were higher at all time points in individuals with ART associated tuberculosis ( P < .001 ) and were associated with areas under receiver operator characteristic curves of 0.90 for RD1 ( 95 % confidence interval [ CI ], 0.78-1.00 ) and 0.92 for PPD ( 95 % CI, 0.83-1.00 ) for the diagnosis of ART associated tuberculosis
Debebe et al., J Immunoassay Immunochem 2010 : A sharp rise in IFN-gamma response to bovine PPD was observed between at week 3, and then from week 3 to 7 post-vaccination, there was rapid falling of IFN-gamma response after which the response remained more or less constant in the consecutive weeks
Sartono et al., PloS one 2010 (Cicatrix) : In a pooled analysis receiving OPV with BCG at birth was associated with significantly lower IL-13 ( p = 0.041 ) and IFN-gamma ( p = 0.004 ) and a tendency for lower IL-10 ( p = 0.054 ) in response to PPD
Burl et al., PloS one 2010 (Cicatrix) : However the IFNgamma : IL-10 ratio positively correlated with TST induration suggesting that the relationship between PPD induced IFNgamma and IL-10 in the peripheral blood may be important in controlling TST reactivity
Wood et al., Vet Microbiol 1994 (Tuberculosis, Bovine) : The problem of false positive reactions, due to the cross-reactive nature of the antigen preparations used, can largely be overcome by using a comparative assay in which an animal 's IFN-gamma response to bovine PPD and avian PPD are compared
Jutel et al., Clin Exp Allergy 1995 : In contrast, PPD induced virtually only IFN gamma secretion
Ebtekar et al., Scand J Immunol 1996 : The PPD1 induced IL-5 production, while the PPD2 induced high levels of IFN-gamma
Saito et al., J Leukoc Biol 1996 (Tuberculosis) : Our present data indicate that TNF-alpha produced by PPD stimulated macrophages and IFN-gamma produced by cell-cell interaction of BCG-immune T cells and antigen engulfed macrophages together activate the macrophages to produce NO
Ng et al., Vet Immunol Immunopathol 1997 (Tuberculosis, Bovine) : Bovine purified protein derivative (PPD) induced interferon-gamma (IFN-gamma) and interleukin-2 (IL-2) mRNA expression was measured in peripheral blood lymphocyte cultures of cattle inoculated with Mycobacterium bovis and compared to cytokine protein levels as measured by IFN-gamma enzyme linked immunosorbent assay and IL-2 bioassay
Nakaya et al., Kekkaku 1997 (Acute Disease...) : Interferon-gamma (IFN-gamma) and interleukin-10 (IL-10) producing ability of peripheral blood plastic-dish adherent cells and non-adherent cells obtained from patients with active pulmonary tuberculosis ( N = 17 ) and healthy controls ( N = 14 ) upon stimulation with purified protein derivatives (PPD) were assessed
Hata et al., Int Arch Allergy Immunol 1997 (Hypersensitivity) : IL-4 pretreatment suppressed PPD induced IFNgamma and IL-5 production but enhanced ECF production
Corrigan et al., Clin Exp Immunol 1998 (Candidiasis, Vulvovaginal...) : Interferon-gamma (IFN-gamma) production in response to both Candida and purified protein derivative (PPD) stimulation was significantly lower in patients compared with controls